DMT is Dimethyl Tryptamine =  N,N Dimethyl 3-amino-ethyl indole.
It is a powerful hallucinogen, the prototype of this class, and
chemically related to psiloc(yb)in and more distantly to LSD.
Dose: around 60 mg.
Method of ingestion: usually smoked (inactive orally at reasonable doses.)
   Can be combined with monoamine oxidase inhibitors (MAOI) to make it 
   orally active and increase the duration.
   Could be snuffed or or injected.
Duration of action: 2-5 minutes of peak, around half an hour of cruise.
Side effects: Stimulation and tactile hallucination during trip. No
   perceivable after-effects. No known long term side effects. May be
   some link with schizophrenia, since it has been detected in vivo.
Status: illegal in USA, Australia, most places.
History: is a component of some snuffs used by South American natives.
         also used in combination with MAOIs (harmaline etc.).
Availability: Very rarely available from dealers; rarely synthesised.
         Available from a range of natural sources.
Psychological effects: A very intense but brief trip, not really
         euphoric. Can be frightening because of the sudden onset.
	 Not really a party drug, rather an interesting experience.
         More intense than LSD, but hallucinations and perceptual
	 changes are of a somewhat different nature.

(these are only my opinions and recollections)

Jeremy
jeremy@rsc3.anu.edu.au [now jgreenw@extro.ucc.su.oz.au -cak]

==========================================================================

------------------------------------------------------------------
     Partial Transcription of a taped workshop with Ethnobotanist,
        Shamanologist, and Psychedelico, Terence McKenna...

                       "Time and Mind"

                  May 26/27, 1990 - New Mexico

The Tykes...

Well, I suppose it's an invitation do describe a DMT trip, which is never to
be passed up. Because I think, I think what we're talking about here is a
continuum, I'm talking about a very narrow band of experience. A continuum of
experience that comes through tryptamine hallucinogens: DMT, Psilocybin, and
the DMT-Harmine combination... and that's it... Mescaline doesn't, isn't what
I'm talking about. Ketamine certainly isn't what I'm talking about. Datura
certainly isn't what I'm talking about. And some of these are plants, and some
of them are synthetic drugs, but it's a very narrow spectrum of these highly
visionary ones, and then the most visionary, the quintessence is DMT. I mean,
I think that DMT is as intense as any drug should ever get; I don't ever want
to be more loaded than that. I don't think you can be more loaded than that
and come back. You know? What happens on DMT for me, and this is based on,
you know, composite image of many experiences, and I've confirmed it to some
degree with other people, but I was talking to somebody the other day,
somebody who had just done it, and I said, "what did you think?" and they
said: "It's the most idiosyncratic thing there is." and I thought, what a
wonderful description, that's exactly what it is - it's pure
idiosyncraticness. It's so idiosyncratic that's all there's there - it's like
idiosyncracy without an object, is what DMT is.

When you smoke this, the onset is very rapid. 30-45 seconds, you know? There's
this feeling which comes over your body - half arousal, half anaesthesia. The
air appears to suddenly have been sucked out of the room because all the
colors brighten visibly, as though some intervening medium has been removed.
And then there's a sound, like a piece of bread wrapper or cellophane being
scrunched up and thrown away. A friend of mine says this is radio-entelechy
leaving the anterior fontanelle at the top of your head. [laughter] I'm not
sure I want to line up with that... but a membrane is being ripped; something
is being torn. And then there is a total (what Mircea Eliade called in a
wonderful phrase) "a complete rupture of the mundane plane". [laughter] You
know? That's like a hit and run accident except the car came from hyperspace,
you know? A complete rupture of the mundane plane. And you fall back into this
hallucinogenic space, and what you see is a slowly rotating red and orange
kind of thing, which, over the years we've nicknamed, uh, 'The Chrysanthemum'.
And it's.. this represents some kind of disequilibrium state that has its
roots in the synapses. What's happening as you're watching this Chrysanthemum
is that millions and then hundreds of millions of DMT molecules are rushing
into these serotonin bond sites in the synaptic cleft and disrupting the
serotonin and switching the electron spin resonance signature of these neural
junctions in this 'other' direction. And this is taking, you know, 30 or 40
seconds, and there's this rising hum, this ____nnnmmmmMMMMMMMM^^^^ that rising
tone; the flying saucer tone of Hollywood B movies... you actually hear this
thing.

And then, if you've taken enough DMT (and it has to do entirely with physical
capacity: Did you take, did you cross the threshold?) something happens [clap]
which... for which there are no words.

A membrane is rent, and you are propelled into this 'place'. And language
cannot describe it - accurately. Therefore I will inaccurately describe it.

The rest is now lies. [laughter] When you break into this space, you have
several impressions simultaneously that are a kind of gestalt: First of all
(and why, I don't know) you have the impression that you are underground - far
underground - you can't say why, but there's just this feeling of immense
weight above you but you're in a large space, a vaulted dome. People even call
it 'The DMT dome' I have said, had people say to me, "Have you been under the
dome?" and I knew exactly what they meant.

So you burst into this space. It's lit, sofeted lighting, some kind of
indirect lighting you can't quite locate it. But what is astonishing and
immediately riveting is that in this place there are entities - there are
these things, which I call 'self transforming machine elves', I also call them
self-dribbling basketballs. [laughter] They are, but they are none of these
things. I mean you have to understand: these are metaphors in the truest
sense, meaning they're lies! Uh, it's a jeweled self-transforming basketball,
a machine elf. I name them 'Tykes' because tyke is a word that means to me a
small child, and I was fascinated by the 54th fragment of Heraclitis, where he
says: "The Aeon is a child at play with colored balls" ... and when you burst
into the DMT space this is the Aeon - it's a child, and it's at play with
colored balls, and I am in eternity, apparently, in the presence of this
thing.

There are many of these things, but the main thing that's happening is that
they are engaged in a linguistic activity of some sort, which we do not have
words for, but it's visible language. They are doing the visible language
trip. When you break into the space, they actually cheer! The first thing you
hear when you pass across is this 'hhhyeaaaaaayyy' - you know the Pink Floyd
song? "The Gnomes have Learned a New Way to Say Hoo-Ray"? This has gotta be
what these guys were talking about; how else could it be? It doesn't make any
sense otherwise.

[laughter]

You break into this space... the gnomes say hoo-ray! And they come rushing
forward and they, and, and the thing then that happens is... and people say
"is there risk, to DMT? it sounds so intense. Is it dangerous?".

The answer is: yes, it's tremendously dangerous; the danger is the possibility
of death by astonishment. [laughter] And you must prepare yourself for this
eventuality, because you are so amazed. Amazement seems to be the emotion that
has torn loose and swamped everything else - I mean astounded? When was the
last time you were genuinely 'ASTOUNDED'? I mean, I think you can go your
whole damned life without being 'ASTOUNDED'... and this is astonishment, you
know, raised to the N-th degree to the point that your jaw hangs...

I mean you're like this:









And it raises issues: like you say, "Jesus, ah, huhh ... I must be dead!" And
you, and the weird thing about DMT is it does not effect what we ordinarily
call the mind. The part that you call "you" - nothing happens to it. You're
just like you were before, but the World has been radically replaced - 100% -
it's all gone, and you're sitting there, and you're saying, "Jesus, a minute
ago I was in a room with some people, and they were pushing some weird drug on
me, and, and now, what's happened? s s is this the Drug? Did we do it? Is this
it?" And meanwhile, these things are saying: "Do not give way to amazement;
Control your wonder." in other words, they try to bring you down. They say,
"Don't just goof out on this; pay attention. PAY ATTENTION... to what we're
doing."  "OK, what're you doing?..."

[laughter]

Say this is what we're doing, and then they proceed to sing
objects into existence. Amazing objects. Objects that are Faberge Eggs, things
made of pearl, and metal, and glass, and gel, and you, when you're shown one
of these things, a single one of them, you look at it an you know, without a
shadow of a doubt, in the moment of looking at this thing, that if it were
right here, right now, this world would go mad. It's like something from
another dimension. It's like an artifact from a flying saucer. It's like
something falling out of the mind of God - such objects DO not exist in this
universe, and yet, you're looking at it. And they're clamoring for your
attention. " 'k at this! 'ook at This! Look at THIS!" and they pull these
things... and each one, you look into it and it begins to open into this
wonder that you must fight. You say "No, don't look at it, look AWAY from it!"
because it's so wonderful that it's swamping my objectivity and destroying my
ability to function in this space.

Well, then they say "do"...

And the objects that they make have the peculiar ability to themselves
generate this linguistic 'stuff' which condenses as other objects. So beings
are making objects, showing you objects, the objects are turning into beings
and making other objects, these beings and objects, they jump into your chest
- and then they jump back out. They jump into your body and disappear into
your body, and then they jump back out, waving these things, just throwing
this stuff in all directions. They are - the word that comes to mind is: they
are Zany. It's like a Bugs Bunny cartoon, uh, gone mad. And all of this energy
- they are elves. This is what elves are.  It's this wierd thing, where they
love you - or they like you a lot, but you can tell that their sense of humor
is Weird.  And that you must be very careful of the deals you cut with these
things. and and in fact I've spent so much time trying to understand what is
this. It has different kinds of feelings about it. One is (and this really
threw me for a loop when I figured this out) after many many of these trips,
and analyzing this place I kept going to, I finally realized: "this place
is... somebody very weird... it's their idea of a reassuring environment for a
human being!  It's like a playpen. It's this warm. well lit, secure, womblike
environment, and when I break into it they these things, the elves and the
toys, are toys!  These are things to amuse me. The way you would hang, uh,
cubes and blocks above a crad... a playpen, you know? Because children are
supposed to coordinate shapes and bright colors. That's what these things are:
they are toys to try and get me to coordinate my perception in this place.
It's a holding area of some sort - someone's created this and is watching me.

OK - that's one metaphor for what it is. Another metaphor is... I took this
stuff to Tibetans, to the Amazon. I gave it to Tibetans, they said "this is
the lesser lights, the lesser lights of the Bardo. You cannot go further into
the Bardo and return. This takes you as far as you can go." When I gave it to
shamans in the Amazon, they said "It's strong - but this is, these are the
ancestors. These are the spirits that we work with. These are ancestor souls.
We know this place." Well then, the third and final metaphor, because when
you're in that place you have such complex emotions - very complex emotions -
something weird is going on with time, because you perceive your body image as
infantile. You seem to have a very large head, and a very body, and very short
limbs. And, you know, I dunno what that's about.

But they're, uh, this...

Then the last facet of it that I want to mention is: there is this 'you must
be on your toes' thing - don't let these guys get behind you. They are tricky.
And their elfin humor may not be your idea of a good time. [laughter]

And I said to myself, where have I had, before, this feeling that I'm having
now. It's a feeling of being with people that I can't trust, but who want to
help me, and who seem to be trying to, uh, cut a deal. That was the word that
gave me the clue: "deal". And then I remembered, "I know where I felt like
this -  I felt like this in the Crawford Market in Bombay when I had a kilo
of Gold in my pocket and I was trying to trade it for hashish, and I was
surrounded by all these Arab hash traders, and they were saying "we're your
friend, just wait, don't worry..." And say "yes, I KNOW you're my friend and
I'm NOT worrying, but, you know, brbrbrrr... perform!" And so then I said:
"Aha the creatures in the DMT flash are Traders..." They're Traders. And
that's what this weird feeling is - it's a business environment in there.
[laughter] We're having a business meeting. THey're saying... and then the
objects! Then I remembered- the objects... they're trade goods! They're
saying: "How about thissss! How about This!".

What do they want? What do I have that they want?... They're meme traders, is
what it is. And I think that what they wanted, and got, and took - without
bothering to even say a word about it - was everything I knew about the
"I Ching". And they're like art collectors. They say "well, the idea is
primitive, and primitive in its execution, but with a certain kind of internal
integrity that one really must respect..." So they're primitive art
collectors, and what they left me with, then, was, uh, my own, you know, their
model of time.  Which is the closest thing to one of these hyperdimensional
objects. The objects themselves cannot exist in this world. But the blueprints
of them can.  And this afternoon, if the computers are up and running, I will
run through this 'time idea' with you.

And I think I will be able to convince you that it has a weirdly crafted
patina to it, that, the feeling is it didn't spring from human minds, it, it
is a creature of another kind of mental universe. And I think, you know, aside
from the crisis on this planet and our own personal difficulties this is the
real challenge of the psychedelic thing; is to meet the inhabitants and trade
with them. And set up a relationship. The notion traders. They can trade
hyperspacial notions from across the cosmos. And this may be all the
extraterrestrial contact that we're, uh, going to be vouch-safed, you know?

\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/

Bob

-- 
Bob Cain    rcain@netcom.com   408-358-2007

There has been an alarming increase lately In the number of things
about which I know absolutely nothing.

===========================================================================


There are three issues here which are a little confused:
1) strength in the sense of effective dose,
2) strength in terms of subjective intensity,
3) being a superior hallucinogen in some subjective sense.

Comparing DMT and LSD, the first is easy.
The effective dose of LSD is around 100 ug, of DMT is around 60 mg,
so in this sense, LSD is a much stronger hallucinogen.

In terms of intensity, they are difficult to compare. Part of the intensity
of DMT stems from the fact that the onset is virtually instantaneous;
one is taken from feeling normal to the peak of the trip in the space
of a few seconds, and this can be totally disorienting and frightening.
DMT does not have the euphoria of LSD, in fact it can be quite
uncomfortable. Also, the smoking of DMT is quite unpleasant compared
with eating some small object. The types of hallucinations experienced
within the peak of the DMT trip differ markedly from those in the peak
of the LSD trip. This difference is very hard to describe, although
one might contrast the dripping flowing colourful experience of LSD
with the DMT visuals in which everything becomes super sharp to the
point of being ripped into fragments, like placing a photo in a blender.
There is some colour enhancement, but it is more like lightning-bolts
of colour rather than flowing ripples of colour, and colours may
be actually entirely changed and several multiple images seen at once.
The 20-30 minute come-down of DMT is similar in experience and intensity
to a small dose of LSD, however one is likely to be too shattered by
the initial peak to worry about this much. The account Bob posted is
highly subjective and metaphorical (as is this one, I suppose) and I
doubt that many people would experience DMT in the way described there.
However, extending the duration of DMT by the use of monoamineoxidase
inhibitors (Ayahuasca,Yage,etc.) is supposed to be a very intense
experience and could give one time to become more involved in it.
It is possible to lose all contact with the senses and the world
briefly while on DMT, as it is, e.g. from a combination of nitrous
oxide and LSD. Also, psiloc(yb)in seems to have some similarity to
DMT whilst retaining similarity to LSD, in that during the psilocin
experience one can be transported into a different reality, although
one which is still definitely based sensually on this one, and
not be able to remember or understand everday reality.
Other hallucinogenic experiences, e.g. the delerium caused by
anti-cholinergics, might be still more intense than DMT in terms
of being completely removed from traditional reality, but I don't
think anyone would recommend experimenting with these dangerous
substances.

In terms of which is the superior hallucinogen, it depends on your
taste. DMT is very interesting and extremely intense, but not 
necessarily pleasant. LSD has more potential for pure recreation.
Most people would probably prefer LSD as a recreational hallucinogen,
and it would be ill-advised for someone who was not very familiar
with coping with the intensity of LSD to be thrust into the
intensity of DMT. On the other hand, if you don't like DMT, you only
have to hang on for a few minutes, whereas if you don't like LSD
you have to hang on for several hours.

This is, of course, apart from the dosage, all subjective.

Jeremy
jeremy@rsc3.anu.edu.au [now jgreenw@extro.ucc.su.oz.au -cak]


=========================================================================


152.94.1.10 (L`HOMBRE INVISIBLE) writes:


>INDOLE ETHYLAMINES
>------------------
>Many plants contains psychedelic tryptamines :

> Piptadenia Peregrina
> Phalaris Grundinacea
> Mimosa hostillis
> Desmanthes illioiensis
> Arundo Donax
> etc.

>The DMT/5-methoxy-DMT ... is often located in the roots of the plant

Depends on the species - some contain it in the leaves or the bark.

>My question is :
>Is it possible to smoke the plant-material directly or do you have to
>exctract
>it first ?.

I don't know as much about 5-Me-O DMT as DMT. THere is an important
difference, which is the dose. The former is effective at about
5mg-10mg from memory, the latter at 30-60mg. Thus, it is possible
to obtain sufficient 5-Me-O DMT from smoking some impure unrefined
sources (such as the poison of Bufo alvarius)..
Considering DMT as opposed to 5-Me-O DMT (which is IMHO by far
the more desirable material), and recalling that most people
find the peak of a DMT trip only to last a very few minutes
after smoking (i.e. you have to smoke it all at once, within
a few tokes, to obtain the peak) you can easily calculate the
necessary purity. Let us say, that one is capable of smoking
100mg of material in a few seconds. THis means that a DMT
containing mixture should be at least 30% pure to get sufficient
effect, and a 5-Me-O DMT mixture should be at least 5% pure.
In actual fact, it is not quite as bad as this, because if
you are using a free-base pipe, you can get away with lower
purities because the DMT is quite volatile, so initially, the
smoking process will concentrate the DMT. 

Comparing this to plant matter, which might be e.g. 0.3% DMT,
and you see at once, that you would need to smoke about 10 g
in a few seconds which is unrealistic. Hence, chemical
purification is necessary. 

The alternative is to take the plant source orally in
combination with the hallucinogenic monoamineoxidase
inhibitor harmaline (and related alkaloids). These
are most readily obtained from Peganum harmala
(or Banisteriopsis caapi) and serve to activate and
potentiate tryptamines, increasing intensity and
duration and giving oral activity to DMT.

> What are the effects (Like the pure stuff (DMT)) ?

A small amount gives a wierd feeling in the body and some
perceptual change. A larger amount gives strong body feelings
and heavy visual effects , somewhat similar to LSD, but
much more based around geometry, and changes of shape
perception. A very large dose is totally awesome, and
people's responses differ, from catatonia, to screaming,
to total ecstasy. Some people describe it as a religious
experience. Many people find they completely leave our
universe for the duration, which is generally up to 5 
minutes, with residual effects up to half an hour.
B
>Which plant(s) are best suited ? (Highest in DMT)

There are various possibilities. Since chemical purification
is generally necessary, the plant content is not vitally
important. Most important is supply - the best species
is one which grows locally, and in the US, the best
source is probably Desmanthus illinoensis.

If you wish to receive instructions on how to chemically
purify DMT from a plant source, and more information about
the effects of DMT, mail me at:
jeremy@rsc3.anu.edu.au [now jgreenw@extro.ucc.su.oz.au -cak]
but do not hassle the owner of this account by replying to
this address.

Jeremy


===========================================================================


{In article <1992Dec22.212054.16140@shearson.com>, curious@somewhere (Curious Furious) writes:
> 
> Hi knowledgeable folks,
> 	I have a few questions from a FOAF:
> 
> 1) When smoking DMT what is the LD50 ? Can it cause a heart attack?
>
Certainly much higher than the amount beyond which one would have
no concept of what a pipe, DMT, oneself, etc. is. Also much higher
than the amount one could get into ones body by smoking before
it was metabolised. I imagine that even if one hooked oneself
to a machine which continously fed oxygen, nitrogen, and DMT
vapour it would still be hard to _physically_ overdose.
As for heart attack, I have no idea. I can imagine being
scared to death (literally).
 
> 2) Has anyone tried doing DMT while on MDMA ? Any complications ?

No idea. However, one of the most striking things about DMT is its
brutalness - the rush from completely baseline to another
universe in about five seconds. Starting off baseline does
little to alter the peak (which tends to override anything)
but alters the severity of the onset.
> 
> 3) Has anyone tried doing DMT while on 'rooms? Any complications ?

Yup - similar to above, except moreso. It takes a large dose
for the effects of the DMT to become visible over the effects of
the trip (likewise for LSD). Also, it is harder to trip on DMT post
psilocybin or LSD, since there is some cross tolerence.

Some combinations with DMT are worthwhile. A couple of beers
beforehand bluntens and deadens a little which can be very
helpful. A good amount of heads will add to the visual 
impact, and a good amount of hash will ad to the wierdness
and otherness. N2O & DMT is interesting, but the combination
is generally intense enough to cause amnesia, and lack of
any kind of regular consciousness for the period of intoxication.

> 
> 4) In the book _Archaic Revival_, Terence McKenna mentions some studies
>    that found that DMT is produced heavily while in the deepest stages
>    of sleep. Anybody have a reference for that?
           
Interesting concept. Like much of McKenna's work, I expect that
the science to back him up is scanty, non-existant, or
occasionally wrong. Makes for a good story, though.
> 
> 5) Since DMT is a naturally occurring substance in the human body,
>    if a machine was created which could extract DMT from your own
>    blood, would that machine be considered illegal?

My limited understanding of US law suggests that if humans
contain DMT then their entire weight can be counted as DMT
(since the carrier weight can be included)
Such a theoretical machine as you suggest  would be covered by
paraphernalia laws?
> 
> 6) Can any MAOI be used to render DMT active orally?
> 
Lamont is the expert on this, and he says yes. I am not convinced,
and I don't think there is any proper research published on
the subject. Even in the case of the traditional harmaline/DMT
interaction, the scientific data is minimal, and it is surmise
only that the DMT is orally activated by the MAOI effect
of the harmaline and not by some other effect.
I hope someone else will fill in the missing details.
>  
> thank you for your time.
> 
my pleasure.

Jeremy@rsc3.anu.edu.au
(not this address)
> 



With respect to orally activating DMT with an MAOI,
Dennis McKenna has this to say in his '84 review article in J. Psych.
Drugs 16(4):

"The potentiation of the behavioral and pharmacological effects of
tryptamine derivatives by MAOIs has been investigated, although
the specific question of the oral potentiation of DMT and other parenterally-
active derivates has apparently not been investigated.  The effects
of DMT in human volunteers was assessed before and 3 days after treatment
with the MAOI iproniazid (Sai-Halasz 1963). Patients receiving DMT
at a reduced dose following the iproniazid treatment experienced
none of the visual illusions or disturbances of time and space perception
that typify the symptoms of the drug.  They reported only a feeling of
"strangeness."  Patients receiving a dose equivalent to that prior
to iproniazid had a two-phase response.  The first stage was similar
to the usual DMT effects, but less pronounced: illusions and hallucinations
were present but less colorful and only manifested themselves with the
eyes closed.  The second phase was characterized by a persistent feeling
of "strangeness" to which the patients often reacted negatively or 
indifferently.  Based on these trials, Sai-Halasz (1963) speculated
that the reduced effects may have been due to the higher 5-HT
concentration in the brain due to MAO inhibition, thus mitigating the
5-HT blocking effects of DMT.  This speculation was also supported
by the observation that prior administration of 1-methyl-d-lysergic acid
butanolamide, a powerful serotonin antagonist, greatly exacerbated
the psychotomimetic effects of DMT (Sai-Halasz 1962)."

So, it would appear that the answer to question 6 hasn't been established.
However, some studies (mentioned above) seem to have been done demonstrating 
an interaction between MAOIs and DMT.

Jeremy handled most of those questions better than I could, so I
don't have much else to add. I doubt there have been any deaths
attributable to DMT use.  Also, I don't recall endogenous DMT in humans
and Dennis doesn't mention it in his review article so it is either
recent (post 1984) knowledge or it is a misprint by the poster or
publisher and should refer to a related tryptamine.  Or maybe it's
another revalation from the self-constructing machine elves.

    --M@


===========================================================================


well i went to Melbourne recently, (so recently i got back yesterday) and
i had the "opportunity" to try DMT.  i smoked it as crystals through a
crack pipe, and this is what i can remember: i had 3 and 1/2 maybe 4 tokes
before i couldn't smoke anymore.  this took about 20 seconds.  everything
around me faded out, and a guy shouting in the distance sounded like he
was shouting from a subway, (echoed).  the guy i was with told me to get
up and run around, and when i did that everything started melting and i
lost the outside world completely.  i thought that this is what it is like
to be god, i was very scared, there where two sort-of thoughts in my mind:
this is what a bad trip is like, and then i thought if this is a bad trip
then it can't hurt me cause it is all in my mind.  then i lost that
thought, and i have sitting in the middle of a great calm.  sitting
figuratively, cause i didn't have a body.  i opened my eyes, and i
had a glimpse of the outside world, for the breifest instant, and then
it started to move like a living moving escher picture. and it was
completely alien.  then i closed my eyes, and i saw these interlocking
frames of gold moving into each other and i was moving into them.  i
thought that i had been inside this place for eternity, and i thought that
i was never going back (to where?) i must have still known that there was
somewhere else.  i completely forgot words.  i couldn't think of what
things were because think of what to call them.  yesterday (three days
later), i was still remembering words.  the first that i remembered was
mother.  but i couldn't remember who she was.  i couldn't remember who i
was.  and then i slowly came back to reality.(Virtuality) i realised
that i had a body and the thing that i was staring at was my own leg.
i don't think that my Virtuality will ever be the same again.
nothing can prepare you for utter devastation, which is DMT, unless you
take lots and lots of LSD maybe.  i have taken that much LSD, cause my DMT
was nothing like.  my advice is to take it, with someone you trust in a
quiet, safe place.  and just do it man!  :)
see ya round the traps, and Don't Eat the Datura!  (you have to smoke it)

--
   The opinions expressed are not necessarily those of the University of
     North Carolina at Chapel Hill, the Campus Office for Information
        Technology, or the Experimental Bulletin Board Service.
           internet:  laUNChpad.unc.edu or 152.2.22.80


==========================================================================


This is from _The Psychedelic Guide to the Preparation of the
Eucharist, in a few of its many guises_, as edited by Robert
E. Brown and associates of the Neo_American Church League for
Spiritual Development & the Ultimate Authority of the Clear
Light (1968), 2nd edition (1971) 


DMT Synthesis

STEP I

     Using an area of good ventilation or a fume hood, place a
1000 ml two hole roundbottom flask in an ice bath using the
setup in Figure II (you want a wobble stirrer in the top hole
of the flask, and a separatory dropping funnel into the side
entry). Add 400 ml cold anhydrous ether to the flask, in which
60 g indole is then dissolved, using the stirrer. To 100 ml
anhydrous ether in a separatory funnel add 50 g oxalyl
chloride. Slowly drip this solution into the vigorously
stirred indole solution over a period of 10 to 15 minutes.
Continue stirring 10 minutes longer. Allow the precipitate to
settle a few minutes and decant the liquid. Add anhydrous
ether and mix well. When satisfied as to the purity of the
precipitate, leave the golden precipitate in the flask for the
next step, which must follow immediately. Yield is
approximately 100 g.

STEP II

     Dimethylamine reacts readily with indole oxalyl chloride.
Use about 400 ml ice cold anhydrous ether in the same 2 neck
1000 ml RB flask used in Step I, with the precipitate in it
from Step I. Cool the ice bath further by using salt and ice.
Estimate the weight of the precipitate and use 100 g indole
oxalyl chloride. For this weight of IOC use two entire 50 g
containers of diethylamine since it will not keep if the
container seal is broken. Cool the amine in container much
below 0 C and dissolve 1 part amine in 3 parts anhydrous cold
ether. Amine may be stored in this solution. For use, warm
stock solution to room temperature and use the appropriate
aliquot. Set up the entire apparatus the same as when adding
the oxalyl chloride. Add the amine solution slowly to the IOC
with vigorous stirring. Stir for 1/2 hour after the addition
is complete. Vacuum filter the precipitate, using ether as a
wash. It is better to slurry the ether water with the
precipitate before filtering [method used]. Recrystallise from
hot ethanol or from a 50-50 methanol-benzene mixture.

STEP III

     Prepare apparatus as in Figure II (1-hole 1000 ml RB
flask set in heating mantle on magnetic stirrer with stir bar
in flask, and condenser inserted into top of flask). Prepare
the indole glyoxyl amide by melting and casting into sticks if
ether is to be used as a solvent. Aluminium foil makes a good
mould for casting pieces that will fit through the condenser.
Also a Soxhlet extractor may be used to add the crystals by
slow solution into the ether. Tetrahydrofluran, if available,
dissolves IGA and the compound is added slowly in the solution
form [method used].

     To a stirred mixture of 15 g LiAlH4 in 100 ml anhydrous
ether (or THF [used]) slowly add the sticks (or solution
[used]) of IGA until 20 g have been added. Keep the rate of
reaction at a reasonable rate or boil-over may occur [do
say!]. Stir and reflux for 90 minutes after the addition is
complete. Cool in an ice bath and begin to cautiously [do
say!] hydrolyse with chips of ice or a cold solution of
methanol, added through the condenser. When there is no
further reaction, add a few ml extra water and allow to settle
finally and decant the clear liquid into an evaporating
vessel. Filter the residue and wash several times with
ether-methanol or THF-methanol [used]. Evaporate the combined
extracts and if necessary, seed the heavy syrup with crystals
of DMT. With no seed crystals the product may take days or
even weeks to crystallise [weeks]. This crude product is
adequate for smoking [do say!]. In order to purify DMT, begin
after the LiAlH4 has been hydrolysed with methanol. Add 500 ml
satd. Na2SO4 solution, mix and filter. Wash with ether or THF
and neutralise the filtrate with 0.1 N HCl. Extract with ether
in a separatory funnel and neutralise the lower layer with 0.1
N NaOh, extracting this solution in turn with chloroform. The
chloroform layer is dried over anhydrous Na2SO4, concentrated,
and from it DMT crystallises on addition of petroleum ether.
The mother liquor can be chromatographed on an alumina column
using benzene-methanol in a 99.8 to 0.2 ratio. [This last
purification is quite difficult.]


-- 
John Collier 			Email: jcollier@ariel.ucs.unimelb.edu.au
HPS -- U. of Melbourne		  	Fax:   61+3 344 7959
Parkville, Victoria, AUSTRALIA 3052

=============================================================================

Newsgroups: alt.drugs
From: jgreenw@extro.ucc.su.OZ.AU (Jeremy Greenwood)
Subject: Re: DMT Ingestion Methods
Message-ID: <1993Jul1.145335.13563@cltr.uq.OZ.AU>
Date: Thu, 1 Jul 1993 14:53:35 GMT

DMT is a powerful hallucinogen. No one should take it for granted
or use it lightly.  It is also illegal, although natural sources
are uncontrolled.

In article <1993Jul1.020634.2524@mixcom.mixcom.com> Nathan.Bowen <Nathan.Bowen@mixcom.mixcom.com> writes:
>    Lately, there has been an increasing interest among alt.drugs 
>posters concerning DMT in its many forms.  I'm finding the many accounts 
>of experiences quite intriguing, but I am still pretty thoroughly in the 
>dark concerning methods of usage.  I believe I understand to a 
>reasonable extent the various methods themselves, but I cannot find 
>sufficient information on the benefits or drawbacks of them.  I seek 
>both scientific evidence and subjective reports of the desirability of 
>given methods from people who are in a position to know.
> 
>    In my understanding, eating/drinking is probably the least desirable 
>method, in that it requires a monoamine oxidase inhibitor to be active 
>orally.

Each method of ingestion has its own advantages and disadvantages.

Oral DMT/harmaline is potentially the best method of ingestion
in terms of having a truely profound experience of useful duration.
Coming on to the experience a little more slowly gives the user
some time to adjust and to cope with and explore the altered state.
Oral DMT is probably the only viable route for most alt.drugs
readers, who can obtain the plants but who don't have the necessary
experience and equipment to sufficiently purify DMT for smoking,
and who do not have access to synthetic DMT.
Unfortunately, the liquors produced by boiling up plant DMT
sources may well make the user puke.

 Although an account of a very successful ayahuasca experience 
>was recently posted that confirmed the possibility of desirable effects 
>resulting from oral consumption, the prolonging effect of the 
>preparation involved seems to undermine the highly-acclaimed temporariness 
>of the DMT experience (hence the Businessman's Trip).  
> 
Well, the temporariness makes the intensity bareable when the
material is smoked. The oral experience is gentler, but just
as profound, if not moreso. Smoked DMT is so brutal, and the 
effect can be so profound, that after much experience, all I 
could say was that I couldn't say anything adequate about it, 
and so I gave up on it.

>    The most common form of ingestion, at least among the accounts on 
>the 'net, is smoking. There are inherent disadvantages to inhaling the 
>gases given off by burning matter, but I don't see any way around it, 
>and it seems that smoking is also the most accepted method for a 
>pleasurable experience.

Don't make the mistake of calling DMT pleasurable - that may
or may not be one of its side-effects :). In fact, 
apart from the physical, smoked DMT is more likely to be
dysphoric than oral DMT. A single user may have one DMT
trip which is totally orgasmic, and then another which is
totally horrific, and then another that is neither.
Smoking the chemical is particularly unpleasant to the
mouth, throat, and lungs, and some people find it an
impossible task.

  I don't see how, logically, a water bong or 
>some such device could be implemented here, but I'm definitely willing 
>(and eager) to be proven wrong.
> 
Hot DMT vapours are somewhat soluble in water; if you are smoking
the chemical, then mostly what you are getting is its vapour, and
there is little you can do to improve the quality.

>    The other methods that have been mentioned are snuffs (a la the 
>native South American rituals)

The South American snuffs contained various tryptamines. It is
well nigh impossible to get a sufficient dose of DMT from a
snuffed plant source - the concentrations just aren't high 
enough. Likewise smoking a plant. The major active in the
snuffs was probably 5-MeO-DMT.

 and injection (for which I can find no 
>references).

Lots of experiments in the 60's. If you have something pure
enough to inject, you might as well smoke it and save yourself
the hassle. Likewise, there is probably little advantage to
snorting the pure chemical over smoking it.

Jeremy

=============================================================================

Newsgroups: alt.drugs
From: pierre@media.mit.edu (Pierre St. Hilaire)
Subject: Re: DMT Ingestion Methods
Message-ID: <1993Jul1.145039.5758@news.media.mit.edu>
Date: Thu, 1 Jul 1993 14:50:39 GMT

>    The other methods that have been mentioned are snuffs (a la the 
>native South American rituals) and injection (for which I can find no 
>references). The snuffs have been reputed as bringing on rapid and 
>powerful effects, and that seems to correspond with my knowledge of 
>snuffed/injected drugs.  I do not, unfortunately, have a sufficient 
>amount of information on the safety of these methods.  I do understand 
>the inherent dangers of sending the material directly to your 
>bloodstream, in that any impurities will follow just as easily.  Other 
>than that, I am fairly in the dark.  This is where the bulk of my 
>request lies.  Are these methods as efficient and desirable as they seem 
>at the outset?  And, even if they aren't, how do they rank with oral use 
>or smoking?  Opinions are as welcome as facts, and any reply will be 
>greatly appreciated.  If I get a large enough response, I'll try to 
>compile a FAQ or short informational file of some sort.
> 

	My experiences and those of others point to the fact that the
subjective effects of tryptamines vary markedly with the route of
absorbtion. While smoking often results in overwhelming experiences it
is possible to have more psylocibin like effects by snorting or eating
small amounts in conjunction with P harmala seeds. It seems also that
5-MeO-DMT and DMT, whose effects differ considerably when smoked, seem
to "converge" in subjective effects when taken orally. I wonder if
other knowledgeable people on the net could substanciate that last
claim.

	Of all the psychedelics, short acting tryptamines seem to have
the most non linear dose-responses curve. Taking twice a barely active
dose will often result in an intense experience! That is the reason
why you should be very careful when taking them orally.

	I recently found a very interesting and potentially safer way
to use 5-MeO-DMT. The key is to dissolve it in distilled water and put
the solution in one of those nose spray bottles in such a way that
each inhalation will dispense about 3-4 mg (Don't screw up there!).
When taken as a nose spray the effects come on more slowly than smoked
(about 1 min. instead of a few sec.) and the effect is more spread out
in time. The nice thing is that it is possible to very accurately
control the dose, which makes the trip a lot more manageable. Taken in
that manner, the effect can be fairly similar to psilocybin, with the
advantage that it is possible to come down within half an hour. I
guess this method could be used with DMT, but you would probably have
to convert the base into a salt (for higher solubility) since you need a
10x higher concentration of DMT in the solution.

					Pierre St Hilaire
					MIT Media Lab



