From: robgood@bestweb.net   
      
   On Saturday, October 10, 2020 at 5:57:11 PM UTC-4, bil...@shaw.ca wrote:   
   > On Saturday, October 10, 2020 at 8:33:34 AM UTC-7, Bob wrote:   
   > > On Friday, October 9, 2020 at 1:58:53 PM UTC-4, Howard wrote:   
   > > > One of the side effects of Trump's treatment is reported to be the   
   > > > potential for mood altering effects of steroids.   
   > > >   
   > > > I know 'roid rage is supposed to be frequent among pro wrestlers and   
   > > > bodybuilders, but I'm curious if anyone has experience with mood effects   
   at   
   > > > therapeutic doses. I know a couple of people who have taken steriods for   
   > > > anti-inflamatory purposes who say they didnt notice anything, but that is   
   > > > of course not a full sample.   
   > >   
   > > You can add me to your sample of those who got no mood effects, even when   
   the dose was high.  I don't know of anyone who's gotten such effects.   
   >   
   > Now you do. My wife took high doses of prednisone quite a few years   
   > back when it was being used to treat multiple sclerosis. It usually   
   > worked to knock down an exacerbation, but it made her very speedy,   
   > she got little sleep and that made her cranky. Indirect mood effect,   
   > I guess.   
   >   
   > But the roid rage being talked about was likely due to longer-term use   
   > to aid muscle-building. My wife would be prescribed a four-day   
   > course and done.   
   >   
   > bill   
      
   Large class, steroids.  It's a chemical class, not a pharmacologic one.    
   Vitamin D's a steroid, for instance.   
      
   In 2018 I was on Solumedrol for a few days intravenously and then prednisone   
   at a high dose, to be tapered over a couple of weeks, orally, for a case of   
   bronchiolitis from parainfluenza B.  I'd taken prednisone previously for   
   bronchitis, lower dose and shorter time.  This time it got rid of my rhonchi   
   but led to rales from congestive heart failure.  I'd been in atrial   
   fibrillation from the chest disturbance, recurring quickly after cardioversion   
   when I was discharged from the hospital, and the combination of A fib and   
   reduced cardiac output led me to gain 22 lbs. of water.  Because in addition   
   to the antiinflammatory, glucocorticoid action, prednisone has s   
   dium-retaining,   
   mineralocorticoid action.  That's the usual concern, not psychic effects.   
      
   Bob in Andover   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)