From: nospam@needed.invalid   
      
   On Tue, 12/17/2024 1:02 PM, vallor wrote:   
   > On Fri, 13 Dec 2024 21:21:04 -0800, Bobbie Sellers wrote:   
   >   
   >> Hi denizens,   
   >>   
   >> 	I was a constant user of aspirin including St.Joseph's aspirin for   
   >> children from an early age. I used to think it was harmless a minor   
   >> pain killer.   
   >> 	In the 1970s it destroyed my life. I didn't realize it at the   
   >> time as I had a viral infection according to PCP of the moment. I   
   >> was sent home with instructions to drink lots of water and to take   
   >> aspirin. I overdid the aspirin because the fever messed up my head.   
   >>   	I over did the aspirin but did not realize anything was   
   >> wrong until a bit later another month or so when my shins broke   
   >> out in red lumps which is english for Erythema Nodosum. I learned   
   >> about by visiting San Francisco General and had to go repeatedly   
   >> before they loosened their tight asses and prescribed a cortisone   
   >> by mouth for my red lumps and learned that I was sensitive to all   
   >> the drugs in the same chemical group as aspirin which is all the   
   >> Salicylate drugs. Salicylates also occur in fruits and vegetables.   
   >> 	Ok so then I got allergic to wheat, animal dairy products   
   >> but specifically those with animal casein. Originally this was   
   >> just cows milk but after a few years I became allergic to goat   
   >> milk and sheep milk cheese.   
   >> 	Then when I was 46 I got very ill maybe from exertion   
   >> but after that whenever I exerted myself I ran the risk of   
   >> being terribly ill. Worse exercise which had been my friend   
   >> since young adulthood became poisonous to my body.   
   >> 	Now this used to be called Chronic Fatigue Syndrome   
   >> but I prefer Systemic Exertional Intolerance Disease. It happens   
   >> after an illness which seems to resolve but recurs when   
   >> exercise is attempted.   
   >> 	At times I thought it was over and would go out as   
   >> I was used to doing for the first part of my life and make   
   >> myself sick all over again. And it causes brain fog which   
   >> is why I did not figure out that exercise was making me   
   >> ill.   
   >>   
   >> 	Legal over the counter drugs can destroy your life   
   >> so be careful. There is no cure for this post-viral problem.   
   >> I had to give up many things like motorcycling and driving.   
   >> I had to give up the motorbikes because I was getting cramps   
   >> in my throttle hand and a bit later gave up driving because   
   >> I could no longer stay awake enough to drive. I have lived   
   >> in the same studio apartment now for over 50 years and it is   
   >> crammed full with stuff of great interest to me at one time   
   >> which is now just somewhat valuable clutter.   
   >>   
   >> 	I have told my tale, heed it and tell it to people   
   >> who think that OTC drugs are safe. Remember that alcohol   
   >> is legal and can be simply deadly or destroy your health   
   >> just like tobacco.   
   >>   
   >> 	bliss-the hobbler   
   >   
   > Hi Bobbie,   
   >   
   > My heart goes out to you.  Sorry you've been going through all that.   
   >   
   > The story has, though, cast a pall over the newsgroup, at least   
   > from my perspective.  Human frailty being what it is, I can understand   
   > the necessity of getting the story out there -- but I wondered if you have   
   > something to say about Ubuntu? :)   
   >   
      
   The "fever" might actually have been an aspirin overdose.   
      
     https://en.wikipedia.org/wiki/Salicylate_poisoning   
      
   And this is Bobbies condition, right here. Right at the   
   end of that article, it vectors off to this article.   
      
   https://en.wikipedia.org/wiki/Reye_syndrome   
      
      "The cause of Reye syndrome is unknown.[2] It usually begins shortly after   
       recovery from a viral infection, such as influenza or chickenpox.[1] About   
       90% of cases in children are associated with aspirin (salicylate) use.[2]   
       Inborn errors of metabolism are also a risk factor.[3] The syndrome is   
       associated with changes on blood tests such as a high blood ammonia level,   
       low blood sugar level, and prolonged prothrombin time.[2] Often, the liver   
       is enlarged in those who have the syndrome.[2]   
      
       Prevention is typically by avoiding the use of aspirin in children.[1] <===   
      
       When aspirin was withdrawn for use in children in the US and UK in the   
   1980s,   
       a decrease of more than 90% in rates of Reye syndrome was observed.   
      "   
      
   Acetyl salicylic acid is also an antiviral, and has some sort of RNA activity.   
   It might have been used for that, if not for the contraindications of Aspirin.   
   Aspirin kills viruses, but it also seems to have other effects. This means   
   it has too many non-specific effects perhaps, to be consumed like popcorn.   
      
   https://pmc.ncbi.nlm.nih.gov/articles/PMC5155651/   
      
   *******   
      
   I think Bobbie is focusing on the wrong thing here. Organic chemistry   
   is of relatively recent origin. Chemists started extracting things from   
   coal tars and crude oil. The chemists were so stupid at the time, as to   
   sniff and (ugh) taste the purified materials extracted. Some of the   
   materials extracted were carcinogens. As a chemist, we give a tip of the   
   hat to those dead people, because they effectively taught us some   
   new behaviors in chem lab -- you don't "inhale" from the vat,   
   neither do you "taste" anything you make. We also learned from that   
   early chemistry, that "anything with a chlorine or a halogen bonded   
   to it, regard it as a carcinogen before determining otherwise".   
      
      "By 1899, Bayer had dubbed this drug Aspirin and was selling it globally."   
      
   Aspirin was likely invented before a lot of our other pharmaceuticals.   
   The testing process for proving a compound is "safe and effective",   
   was likely a lot more crude and not very good.  This means we "accepted"   
   the material, without a thorough workup. Modern drugs go through a lot   
   more testing steps than the Aspirin described in Wikipedia.   
      
   There are currently around 20 million organic compounds. We've made so   
   many of them, that some, they have a name and a melting point, and no   
   other determination of properties has been done. We don't ingest these.   
   The number of materials commonly in circulation, is a lot less than that.   
   And orders of magnitude less, are used as therapeutic drugs.   
      
   When the radioactive material "radium" was in vogue, some genius added   
   it to a cough syrup. Some gentleman consumed a quantity of the material...   
   and his jaw fell off (lower jaw detached). This put a damper on the   
   consumption of the medication. Now, that's how we used to do things :-)   
   That, and having fluoroscopes in shoe stores, so you could look at   
   your toe bones inside a new pair of shoes (XRays). Humans really aren't all   
   that bright, when you get right down to it.   
      
      Paul   
      
   --- SoupGate-DOS v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)