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|    Message 8,220 of 8,965    |
|    MrPostingRobot@kymhorsell.com to All    |
|    DNA surveys make doom surveys and sample    |
|    31 May 21 05:38:34    |
      People have told me in the course of something I was doing at the time       that DNA evidence decays rapidly. But it also depends on where it was found       and what kind of purpose it's being put to. 98% of human DNA is random       junk. It's left over from our individual human inheritance and       some is there from our evolutionary history. It's theorize the historical junk       can come in handy every now and then if a part of it can be "re-activated"       and protect someone against a virus their family or species saw       in the past. Or one that may have just evolved from an old one our DNA saw.              But I also ran across at least one authoritative estimate of how       long DNA lasts "on average" which with a lil math explains why       "alien DNA" (presumably if by some freak chance DNA is not just specific       to Earth as current evidence suggests) has not been found and       why DNA surveys of Loch Ness might find nothing interesting but a bunch of       eels.               Boston Strangler Case: How Long Does DNA Last?        Live Science, 12 Jul 2013        Last year, researchers estimated that the half-life of DNA - the point at        which half the bonds in a DNA molecule backbone would be broken - is 521        years. That means that, under ideal conditions, DNA would last about 6.8        mn years, after which all the bonds would be broken.              So the "estimate" is that 1/2 the DNA "links" will be broken after 512y.              Sounds a long time. Some magazine articles say DNA "can last mns of years".       But that is mostly hype.              Let's see what time does to human DNA. Human DNA contains a surprisingly       small number of genes -- about 30k define the structure of our body       and brains and enough personality traits to get us into a sh*tload       of trouble when we exaggerate on USENET.              According to the cite after 512y only (on average) pairs of base pairs       are left. It turns out to be unlikely any complete genes are left       because many are so big.       On average "every other link" between base pairs has broken down.       This means after 512y there is almost certainly not enough info       left to even ID a DNA sample as human. But if you have other information       to assume it was human then there still might be enough to ID the sex       or hair color from unique relatively short sequences that are normally       present. But this procedure will be counfounded by the junk DNA       that is 50 times more common than the "real DNA" in our genomes.       I.e. there are gunna be a lot of false positives to any test.              We can make a table to show the situation over time:              After How many bp are random bits of DNA       512y -> "every 2nd link broken" -- average length of strand ~2 genes       256y avg len 4 genes       128 8       64 16       32 32       16 64       8 128       4 256       2 512       1 1024              So just using simple "halflife" definition we can deduce that after 12m       DNA has broken into approx 1000 bp chunks. Unfortunately this is       on average only 1% of what you need to find a single (average) human gene.              After, eg ~50y, chunks are only 16 bp long on average. Only if you have       some other information that says the sample is e.g. human might and it's only       might be able to find genes that contain unique sequences of 16 bp.       And because of junk there are big caveats.       Other things you cannot determine "at all".              The situation is actually much worse than this. First, the "521y"       is based on average conditions. If the sample is subject to sunlight,       heat, or water (and I presume seawater even more) it will degrade faster.               DNA degrades over time, and just how long it lasts depends on how well it's        preserved. Factors such as exposure to heat, water and sunlight can cause        the molecule to degrade faster, according to Slate.        -- LiveScience, "Boston Strangler Case...", 12 Jul 2013              And then there again is the "junk DNA" aspect. Only 2% of human DNA actually       code for protein/characteristics. The "junk" can be used to identify family       connections because it gets inherited (with noise), but whether the DNA is       from a male or female requires correct ID of the X and Y chromosomes.       Since there is some much junk we can be much more certain if an       individual matches a given family profile than we can in deciding whether       the sample comes from a redhead or a male.              Since a (normal) human has 23 pairs of chromosomes each is around       30k/23 = 1300 genes long.              Unless you get a lucky break you might need as many as ~650 genes to       definitely ID some sample as e.g. human.              There are ~3 bn bp in human DNA so discarding 98% as junk we get an       average gene size of .02*3*10^9/30000 = 2000 bp.       Meaning 650 genes is around 1.3 mn bp long.              I.e. even after 1-2 y it maybe impossible to ID species from       "wild dna survey" or random sample.              If Nessie is only a sometimes visitor to that Scottish lake then       it might leave no findable DNA behind to survey.                            --       Upcoming events:       9 Jul 2021 NOAA bn Dollar Disasters Q2              "Online Haters" Are Psychopaths, Recent Study Finds.       The Debrief, 6 Apr 2021       Recently published research finds that "online haters" or people who       post hateful comments on online forums and social media demonstrate       high levels of personality disorder traits associated with psychopathy.              'I can't imagine they're nice': Sci-fi creators weigh in on aliens,       impending UFO report       NBC News on MSN.com, 27 May 2021 14:24Z       The US govt is finally starting to publicly acknowledge UFOs.       The creator of "The X-Files" has been waiting for this ...              Extraordinary explanations for UFOs look increasingly plausible       The Hill, 27 May 2021 21:46Z       Any revelation that Russia or China has developed technology capable of       defying the laws of physics and aerodynamics would ...       [Dont worry. Putin is only 1000 years ahead of US military tech.       You can catch up by April]!              Britain's X Files: Government's UFO hunters may restart their search for       alien life       The Daily Telegraph, 28 May 2021 18:0Z       Dept that once investigated other-worldly sightings in Smethwick and       north London could be revived after Pentagon ...              What the shakeups, legal losses for fossil fuel companies mean for climate       change efforts       PBS NewsHour, 28 May 2021 0:03Z               Why a 'crushing' day for Big Oil represents a watershed moment in        the climate battle        CNBC, 28 May 2021 0:03Z        A series of landmark boardroom and courtroom defeats shows the        growing pressure on international oil and gas companies to set        short-, medium- and long-term ...        [In a shock result an AI s/w I run indicates the change in energy        tech is behind the sudden "change of heart" on UFO disclosure policy        in the US. Nick Pope mentioned "powerful forces" were at work and        it seems this is what might have been between the lines. :) But it        also may indicate nothing will really change because some fossil        companies are transforming to renewables companies and still won't        want to allow or even ack tech 100s of y in advance of theirs].              Newly released radar footage shows UFOs swarming Navy ship, filmmaker claims       New York Post, 28 May 2021 02:56Z       The filmmaker who leaked footage of UFOs harassing a warship off the coast              [continued in next message]              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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