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   rec.drugs.misc      Misc. recreational drugs      5,431 messages   

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   Message 3,924 of 5,431   
   BilZ0r to glog   
   Re: Researchers ID common link to LSD, s   
   12 Dec 03 21:45:02   
   
   XPost: alt.drugs.psychedelics, alt.drugs, alt.drugs.rfg   
   XPost: rec.drugs.psychedelic   
   From: BilZ0r@TAKETHISOUThotmail.com   
      
   Just because it dosn't mean it is inconsequencial to its hallucinogenic   
   action dosn't make it anyless real. i.e. Antihistamines... many of them   
   are taken by people going senile because they have a strong   
   anticholinergic action (which helps in 10% of senility cases). The   
   anticholinergic action is inconsequencial to its antihistaminergic   
   action, but most antihistamines are still anticholinergic.   
      
   Just because a drug binds to a whatever receptor, dosn't make that drug   
   whatever-ergic. LSD decreases the amount of serotonin in the cortex, it   
   is hence, and anti-serotonergic. It increase the amount of glutamate, you   
   -could- call it a glutaminergic then.   
      
   glog  wrote in news:slrnbtjrfo.7jv.be@be.here.now:   
      
   > Once upon a timeless moment,   
   > BilZ0r  hallucinated:   
   >> glog  wrote in news:slrnbtic5s.6jb.be@be.here.now:   
   >   
   >>>> I mean, LSD (and   
   >>>> other indole hallucinogens) are really anti serotonergic.   
   >>>>   
   >>>   
   >>> Huh??   
   >>>   
   >>>   
   >>   
   >> They inhibit the spontaneous activity of the Raphe Nuclei.   
   >   
   > The article you recently posted said "LSD's action at the 5-HT1A   
   > receptor and raphe neurons is inconsequential to its hallucinogenic   
   > action".   
   >   
   >> The only real   
   >> source or serotonin in brain.   
   >   
   > The article you recently posted said "The 5-HT2A receptor, which now   
   > seems to be the only shared and clinically important target of   
   > hallucinogens, has been found throughout the cortex, and particularly   
   > in cortical pyramidal cells.   
   >   
   >   
   >   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)   

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