From: mdhangton@gmail.com   
      
   Dorothy J Heydt wrote:   
   > In article ,   
   > Will in New Haven   wrote:   
   >>   
   >> And Persian cats are beautiful.   
   >   
   > "The smallest feline is a masterpiece."   
   > --Leonardo da Vinci   
      
   From _Breed Predispositions to Disease in Dogs and Cats_,   
   by Alex Gough & Alison Thomas:   
      
   PERSIAN   
   Cardiovascular conditions   
   Hypertrophic cardiomyopathy   
   • Common disease   
   • Middle-aged to older cats predisposed   
   • Males predisposed   
   • May be inherited in this breed   
   Peritoneopericardial diaphragmatic hernia   
   • Accounts for 0.5% of congenital heart disease   
   but may be under-reported   
   • Females may be predisposed   
   • May be inherited as an autosomal recessive   
   trait in cats   
   Dermatological conditions   
   Dermatophytosis   
   • Common   
   • This breed may develop dermatophytic pseudomycetoma,   
   characterised by one or more   
   ulcerated and discharging nodules over the   
   dorsal trunk or tail base   
      
   Systemic lupus erythematosus   
   • Rare in cats   
   • No age or sex predisposition   
   Primary seborrhoea   
   • Rare in cats   
   • Autosomal recessive mode of inheritance   
   Chédiak-Higashi syndrome (blue smoke   
   Persians only)   
   • Autosomal recessive inheritance   
   • See under Haematological conditions   
   Idiopathic periocular crusting   
   • May be associated with Malassezia or feline   
   acne   
   Facial fold pyoderma   
   Idiopathic facial dermatitis in Persians and   
   Himalayans   
   • Uncommon   
   • Unknown cause; possibly genetic basis   
   Multiple epitrichial cysts   
   • Affect eyelids   
   Skin tumours   
   • See under Neoplastic conditions   
   Drug reactions   
   Griseofulvin   
   • Anecdotal reports suggest a predisposition to   
   side effects with this drug in this breed   
   Gastrointestinal conditions   
   Congenital portosystemic shunt   
   • Usually extrahepatic shunts   
   Congenital polycystic liver disease   
   • Breed predisposition   
   • May be associated with polycystic kidney   
   disease   
   Haematological/immunological   
   conditions   
   Chédiak-Higashi syndrome (blue smoke   
   Persians only)   
   • Autosomal recessive inheritance   
   • Abnormal lysosomes and neutrophil granules   
   seen   
      
   Susceptibility to dermatophytosis   
   • Can lead to severe and long-term infections   
   Systemic lupus erythematosus   
   • Rare in cats   
   • No age or sex predisposition   
   Neoplastic conditions   
   Basal cell tumour   
   • Reported to be at increased risk   
   • Average age is 7–10 years   
   Sebaceous gland tumours   
   • Possible breed predisposition   
   • Seen in older cats (average age 10 years)   
   Neurological conditions   
   Lysosomal storage disease – alpha   
   mannosidosis   
   • Inheritance suspected   
   • Rare   
   • Signs seen at 2–4 months   
   Ocular conditions   
   Coloboma   
   • Congenital condition; breed predisposition   
   • May occur in one or more ocular tissues including   
   eyelid, iris, optic nerve and sclera   
   Entropion   
   • Breed predisposition   
   Lacrimal punctal aplasia   
   • Congenital condition; predisposed breed   
   Idiopathic epiphora   
   • Breed predisposition; may relate to head and   
   eyelid shape   
   Corneal sequestration   
   • Breed predisposition   
   Congenital cataract   
   • Rare condition; reported in this breed   
   Chédiak-Higashi syndrome (blue smoke   
   Persians only)   
   • Autosomal recessive inheritance   
   • See under Haematological conditions   
      
   Retinal degeneration   
   • Autosomal recessive inheritance suspected   
   Lysosomal storage diseases   
   • Inheritance suspected   
   • Rare   
   • Types affecting ocular tissues: ?-mannosidosis   
   Physiological conditions   
   Blood group   
   • In the USA 76% reported as group A and   
   24% as group B   
   • In the UK 12% were reported as group B   
   Prognathism   
   • A longer lower jaw than upper jaw is accepted   
   as a breed standard   
   Renal and urinary conditions   
   Polycystic kidney disease   
   • Autosomal dominant inheritance   
   • Cysts arise in both the medulla and cortex   
   and enlarge over time. They may be detected   
   by ultrasound as early as 6–8 weeks of age.   
   Most cases do not develop renal failure until   
   later in life (average age 7 years).   
   Calcium oxalate urolithiasis   
   • Higher incidence reported in this breed   
   Reproductive conditions   
   Cryptorchidism   
   • Suspected inherited defect with a simple   
   autosomal recessive, sex-linked mode of   
   inheritance   
   • Possible breed predisposition   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)