XPost: alt.fan.heinlein   
   From: dtravel@sonic.net   
      
   On 2/15/2026 12:52 PM, William Hyde wrote:   
   > Dimensional Traveler wrote:   
   >> On 2/14/2026 4:13 PM, William Hyde wrote:   
   >>> Paul S Person wrote:   
   >>>> On Thu, 12 Feb 2026 15:09:16 -0500, Cryptoengineer   
   >>>   
   >>>>> While I have a lot of issues with the Catholic church, its   
   >>>>> extreme takes on how close a relative could marry (7 degrees of   
   >>>>> separation) had the good effect of avoiding this inbreeding,   
   >>>>> and also flattening society by destroying the 'hereditary clan'   
   >>>>> or 'tribal' layer of social organization, and encouraging far   
   >>>>> flung social connections.   
   >>>>   
   >>>> Except, of course, for the nobility and the royalty. Hemophilia   
   >>>   
   >>> Somewhere in her family tree, one of Victoria's ancestors, or   
   >>> Victoria herself, had a mutation on her X chromosome which led to the   
   >>> most famous cases of royal Hemophilia.  It was probably Victoria   
   >>> herself or her mother, but it is just possible that it existed   
   >>> earlier and was never passed to a male child.  Unlikely but possible.   
   >>>   
   >>> Queen Victoria had no siblings, but she passed her defective X   
   >>> chromosome to three of her children.  As the elder sons were healthy   
   >>> it did not become clear for some time that she carried the disease.   
   >>>   
   >>> Naturally the royalty of Europe were eager to marry into the royal   
   >>> family of what was then the world's dominant power.  Some did this   
   >>> before the disease was suspected, others took a chance, sometimes on   
   >>> dubious medical advice (carriers generally bruise more easily than   
   >>> non- carriers, and some experts were overconfident of their ability   
   >>> to use this to detect a carrier).   
   >>>   
   >>> Poor Leopold, Alexei and the others were not victims of their   
   >>> ancestor's martial practices. Just of bad luck and sometimes, bad   
   >>> judgment.   
   >>>   
   >> My father was a hemophiliac from this matriarchal carrier type.  (It   
   >> was a factor in his death in his 60's.)  Female children do not have   
   >> hemophilia from this but pass it down.  Male children do not pass it   
   >> down but have hemophilia.   
   >   
   > Male sufferers cannot pass hemophilia onto their sons, as the son's x   
   > chromosome must come from the mother.  On the other hand their daughters   
   > are always carriers (unless they suffer from Turner Syndrome, I suppose).   
   >   
   If I were on speaking terms with her I'd ask my sister about that.   
      
   --   
   I've done good in this world. Now I'm tired and just want to be a cranky   
   dirty old man.   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)