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   sci.med.psychobiology      Dialog and news in psychiatry and psycho      4,734 messages   

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   Oliver Crangle to All   
   What The Nose Knows Of Schizophrenia...   
   11 Aug 14 11:42:01   
   
   From: olivercranglejr@gmail.com   
      
        
   Clinical Trial Results   
      
   What The Nose Knows Of Schizophrenia...   
      
   What The Nose Knows Of Schizophrenia...    
   4/30/2013 2:34 AM ET   
   Schizophrenia, a severe and debilitating mental disorder, is said to affect   
   about 24 million people worldwide. Unlike a majority of medical conditions,   
   which are detected by various methods like blood tests, MRIs and biopsies,   
   schizophrenia is diagnosed    
   only through interviews with patients and through psychological tests, and   
   therefore a definitive diagnosis may be difficult.   
      
   But a new finding by researchers at Tel Aviv University and Johns Hopkins   
   University gives hope not only for a more accurate diagnosis of schizophrenia   
   but also for the crucial, early detection of the disease, paving way for an   
   improved treatment.   
      
   As part of the study, researchers collected samples of olfactory neurons,   
   found in a small patch of tissue on the upper part of the inside of the nose,   
   through a simple biopsy from patients diagnosed with schizophrenia and a   
   control group of non-affected    
   individuals.   
      
   The microRNA profiles of the collected samples were studied by applying a   
   high-throughput technology. The researchers found that a specific microRNA was   
   elevated in patients diagnosed with schizophrenia compared to healthy   
   individuals. Further study also    
   revealed that this particular microRNA controls genes associated with the   
   generation of neurons, said the researchers.   
      
      
   Noam Shomron of Tel Aviv University's Sackler Faculty of Medicine says that   
   finding the timeline of the change in microRNA expression - i.e., finding   
   whether the alteration in microRNA expression begins before schizophrenic   
   symptoms manifest themselves,    
   or only after the disease fully develops, would lead to early diagnosis,   
   better treatment, and possibly even the postponement of symptoms.   
      
   by RTT Staff Writer   
      
   For comments and feedback: editorial@rttnews.com   
      
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