From: unk...@googlegroups.com   
      
   The Microbiome & Autism Series By Teresa Conrick: Part 1 "The Epicenter?"   
      
   Gut-brain   
      
   Note: We have a rich treasure trove of posts from all of our contributing   
   editors, published over the last seven years. During the month of December,   
   we'll be sharing an assortment of posts and series, starting with Teresa   
   Conrick's Microbioeme series.    
   We invite you to use the pull down menus to read material that's new to you,   
   but previously publishesd.  Happy reading.   
      
   By Teresa Conrick   
      
   Since 1938, autism has moved from a blip on the radar screen to a full-force   
   tsunami today.  Those first eleven children identified by psychiatrist, Dr.   
   Leo Kanner, all exhibited the now infamous triad of behaviors:   
      
   Qualitative impairment in social interaction   
   Qualitative impairments in communication   
   Restricted repetitive and stereotyped patterns of behavior, interests and   
   activities   
   Sadly, there is not enough reporting of the  MEDICAL patterns that Kanner   
   briefly described. Dan Olmsted was the trailblazer on the connection of toxic   
   exposure in those families, with his UPI series posted on our homepage.  Then   
   he and Mark Blaxill went    
   back and forth in history to seal the deal on specifically, MERCURY and its   
   insidious relationship with autism.  Andrew Wakefield has been researching and   
   publishing for over ten years on the gut-brain connection in autism.    My   
   gratitude to each of    
   them for their continual investigations.   
      
   Leo Kanner wrote these descriptions of those first-ever, diagnosed children   
   but he did not see the obvious:   
      
   *  "Eating," the report said, "has always been a problem with him."   
      
   *    large and ragged tonsils.   
      
   *    Following smallpox vaccination at 12 months, he had an attack of diarrhea   
   and fever   
      
   *    Large tonsils and adenoids   
      
   *    He vomited a great deal during his first year,   
      
   *    She quit taking any kind of nourishment at 3 months. She was tube-fed   
   five times daily up to 1       year of age.   
      
   *    He vomited all food from birth through the third month.   
      
   *    His tonsils were removed when he was 3 years old.   
      
   *    He vomited all food from birth through the third month.   
      
   *    He suffered from repeated colds and otitis media, which necessitated   
   bilateral myringotomy   
      
   *    Because of a febrile illness at 13 months, her increasing difficulties   
   were interpreted as possible   
      
         postencephalitic behavior disorder.       
      
   *    He had been kept in bed often because of colds, bronchitis, chickenpox,   
   streptococcus infection, impetigo   
      
   Kanner missed the pattern of GI issues and INFECTION.  These two medical   
   problems have continued to be prevalent in many if not most of the children   
   being diagnosed today. Instead, he did the Freudian spin:   
      
   Food is the earliest intrusion that is brought to the child from the outside.   
   David Levy observed that affect-hungry children, when placed in foster homes   
   where they are well treated, at first demand excessive quantities of food.   
   Hilde Bruch, in her    
   studies of obese children, found that overeating often resulted when   
   affectionate offerings from the parents were lacking or considered   
   unsatisfactory.   
      
   Our patients, reversely, anxious to keep the outside world away, indicated   
   this by the refusal of food. Donald, Paul ("vomited a great deal during the   
   first year"), Barbara ("had to be tube-fed until 1 year of age"), Herbert,   
   Alfred, and John presented    
   severe feeding difficulty from the beginning of life.   
      
   The children also seemed to have illnesses that may point to Streptococcus, as   
   evidenced by infection of their tonsils, adenoids and ears. That seems to be   
   the pattern still today, if not more.   
      
   I continue to read more and more research that fits this pattern of infection   
   leading to effects on the brain.  Not enough commensal bacteria and too many   
   pathogens can be the epicenter of inflammation, pain, and metabolic reactions   
   that ultimately reach    
   the brain:   
      
   Researchers have long postulated that gut bacteria influence brain function...   
   In 2011 Mazmanian and colleagues reported that changes in gut microbial   
   composition might have far-ranging effects that extend to the brain.8....   
   "Genes and an environmental    
   trigger are necessary but not sufficient for disease development. We knew   
   there had to be a third key element," says Alessio Fasano, chief of pediatric   
   gastroenterology and nutrition at Mass General Hospital for Children in   
   Boston. Fasano and colleagues    
   hypothesize the answers lie with the health of the gut microbial ecosystem as   
   a whole...   
      
   ..... Research suggests that short-term exposure to xenobiotics alters   
   microbial physiology, community structure, and gene expression.   
      
   What is a xenobiotic? ----"a chemical compound (as a drug, pesticide, or   
   carcinogen) that is foreign to a living organism..  "   
      
   There is growing evidence that both environmental assaults AND vaccines can   
   change the microbiome:   
      
   ..... Colonization is a dynamic process of interactions among microbes and   
   between microbes and the host and result in balanced bacterial ecosystems that   
   benefit health. Perturbations of these interactive microbial structures (e.g.,   
   by environmental    
   change or vaccinations) alter the bacterial network structures and may thereby   
   influence the presence and containment of other microbiota members, and these   
   alterations have effects on health and susceptibility to disease (13,14)."    
      
   Autism - could it be from the downward effect of MAN changing the structure of   
   the microbiome?  From recent investigations:   
      
   The current study confirmed these suspicions, and found that children with   
   autism had significantly fewer types of gut bacteria, probably making them   
   more vulnerable to pathogenic bacteria.... To date, studies of the gut   
   microbiome in autistic subjects    
   have focused primarily on pathogenic bacteria, some of which have been   
   implicated in alterations to brain function. One example involves   
   gram-negative bacteria containing lipopolysaccharides in their cell walls,   
   which can induce inflammation of the brain    
   and lead to the accumulation of high levels of mercury in the cerebrum.     
      
      
   [continued in next message]   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)