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   Diabetes, depression predict dementia risk in people with slowing minds   
      
   Date:   
   February 20, 2015   
   Source:   
   University College London   
      
   Summary:   
   People with mild cognitive impairment are at higher risk of developing   
   dementia if they have diabetes or psychiatric symptoms such as depression,   
   finds a new review. Mild cognitive impairment is a state between normal aging   
   and dementia, where someone's    
   mind is functioning less well than would be expected for their age.   
   Date:   
   February 20, 2015   
   Source:   
   University College London   
   Summary:   
   People with mild cognitive impairment are at higher risk of developing   
   dementia if they have diabetes or psychiatric symptoms such as depression,   
   finds a new review. Mild cognitive impairment is a state between normal aging   
   and dementia, where someone's    
   mind is functioning less well than would be expected for their age.   
      
   People with mild cognitive impairment are at higher risk of developing   
   dementia if they have diabetes or psychiatric symptoms such as depression,   
   finds a new review led by UCL researchers.   
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   Mild cognitive impairment (MCI) is a state between normal ageing and dementia,   
   where someone's mind is functioning less well than would be expected for their   
   age. It affects 19% of people aged 65 and over, and around 46% of people with   
   MCI develop    
   dementia within 3 years compared with 3% of the general population.   
   The latest review paper, published in the American Journal of Psychiatry,   
   analysed data from 62 separate studies, following a total of 15,950 people   
   diagnosed with MCI. The study found that among people with MCI, those with   
   diabetes were 65% more likely    
   to progress to dementia and those with psychiatric symptoms were more than   
   twice as likely to develop the condition.   
   "There are strong links between mental and physical health, so keeping your   
   body healthy can also help to keep your brain working properly," explains lead   
   author Dr Claudia Cooper (UCL Psychiatry). "Lifestyle changes to improve diet   
   and mood might help    
   people with MCI to avoid dementia, and bring many other health benefits. This   
   doesn't necessarily mean that addressing diabetes, psychiatric symptoms and   
   diet will reduce an individual's risk, but our review provides the best   
   evidence to date about what    
   might help."   
   The Alzheimer's Society charity recommends that people stay socially and   
   physically active to help prevent dementia. Their guidelines also suggest   
   eating a diet high in fruit and vegetables and low in meat and saturated fats,   
   such as the Mediterranean    
   diet.   
   "Some damage is already done in those with MCI but these results give a good   
   idea about what it makes sense to target to reduce the chance of dementia,"   
   says senior author Professor Gill Livingston (UCL Psychiatry). "Randomised   
   controlled trials are now    
   needed."   
   Professor Alan Thompson, Dean of the UCL Faculty of Brain Sciences, says:   
   "This impressive Systematic Review and meta-analysis from The Faculty of Brain   
   Science's Division of Psychiatry underlines two important messages. Firstly,   
   the impact of medical    
   and psychiatric co-morbidities in individuals with mild cognitive impairment   
   and secondly, the importance and therapeutic potential of early intervention   
   in the prevention of dementia. Confirming these findings and incorporating   
   appropriate preventative    
   strategies could play an important part in lessening the ever-increasing   
   societal burden of dementia in our ageing population."   
   Story Source:   
   The above story is based on materials provided by University College London.   
   Note: Materials may be edited for content and length.   
   Journal Reference:   
   Claudia Cooper, Andrew Sommerlad, Constantine G. Lyketsos, Gill Livingston.   
   Modifiable Predictors of Dementia in Mild Cognitive Impairment: A Systematic   
   Review and Meta-Analysis. American Journal of Psychiatry, 2015;    
   ppi.ajp.2014.1 DOI: 10.1176/appi.ajp.   
   2014.14070878   
   Cite This Page:   
   MLA APA Chicago   
   University College London. "Diabetes, depression predict dementia risk in   
   people with slowing minds." ScienceDaily. ScienceDaily, 20 February 2015.    
      
      
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