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   Antibiotics raise RISK of diabetes: Shock study reveals link for those taking   
   TOO many    
      
   PEOPLE who take too many antibiotics may be at risk of developing diabetes.    
   By DAVID PILDITCH    
   07:27, Fri, Aug 28, 2015 | UPDATED: 10:11, Fri, Aug 28, 2015    
               
      
               
   23    
   Antibiotics pills    
      
      
      
   People taking too many antibiotics may be at risk of developing diabetes    
   A shocking new study suggests there is a clear link between the disease and   
   the number of times a patient has been prescribed the drugs.    
      
   Those given five or more prescriptions over a period of up to 15 years are up   
   to 53 per cent more likely to develop Type 2 diabetes than those given anti   
   biotics just once or never, scientists have found.    
      
   The researchers in Denmark tracked 170,404 patients with Type 2 diabetes and   
   1.3 million who did not have the disease.    
      
   They found the risk of getting diabetes was highest in those given antibiotics   
   that are effective against a narrow range of bacteria.    
      
      
   Study author Dr Kristian Mikkelsen said: "In our research we found people who   
   have Type 2 diabetes used significantly more antibiotics up to 15 years prior   
   to diagnosis compared to healthy controls."    
      
   Dr Mikkelsen, of Gentofte Hospital in Hellerup, Denmark, said more research   
   was needed because the findings did not prove that the drugs trigger diabetes.    
      
   Antibiotics, the main way of treating infections for more than 60 years, can   
   alter the bugs living in the gut.    
      
      
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   Some of these bugs may contribute to the impaired ability of people with   
   diabetes to metabolise sugar.    
      
   But an alternative explanation could be that people with undiagnosed diabetes   
   may be more prone to infection and therefore use more antibiotics.    
      
   The influence of other key risk factors could not be ruled out and it might be   
   that obesity and Type 2 diabetes cause an increased use of antibiotics,   
   because both are thought to increase the risk of infection    
      
   Dr Richard Elliott, research communications officer at Diabetes UK    
   Dr Mikkelsen said: "Although we cannot infer causality from this study, the   
   findings raise the possibility that antibiotics could raise the risk of Type 2   
   diabetes.    
      
   "Diabetes is one of the greatest challenges facing modern health care, with a   
   globally increasing incidence.    
      
   "Further investigation into long-term effect of antibiotic use on sugar   
   metabolism and gut bacteria composition could reveal valuable answers about   
   how to address this public health crisis. Patterns in antibiotic use may offer   
   an opportunity to prevent    
   the development of the disease or to diagnose it early."    
      
   Type 2 diabetes is the most common form of the condition, accounting for 90 to   
   95 per cent of all cases.    
      
   The lives of four million people in Britain are now blighted by the disease   
   and the epidemic is costing the NHS £10billion a year.    
      
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   The new study, published in the Journal of Clinical Endocrinology &   
   Metabolism, found that people with Type 2 diabetes filled out 0.8   
   prescriptions for antibiotics a year on average.    
      
   In comparison, non-diabetics filled out 0.5 prescriptions a year.    
      
   Dr Richard Elliott, research communications officer at Diabetes UK, said the   
   findings suggest an association between the use of antibiotics and Type 2   
   diabetes.    
      
   But he added: "They do not show that taking anti biotics causes Type 2   
   diabetes.    
      
   "The influence of other key risk factors could not be ruled out and it might   
   be that obesity and Type 2 diabetes cause an increased use of antibiotics,   
   because both are thought to increase the risk of infection.    
      
   "As the researchers themselves suggest, clinical trials are needed."    
      
   The study comes just days after the National Institute for Health and Care   
   Excellence published new guidelines after concerns that doctors are needlessly   
   dishing out up to 10million prescriptions for antibiotics every year.    
      
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   http://www.express.co.uk/life-style/health/601271/Antibiotics-cl   
   e-raised-risk-developing-diabetes-research-finds   
      
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