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   Health   
      
   Head injuries may lead to the development of dementia later in life - even in   
   patients who appear fully recovered   
      
   By Ben Spencer Medical Correspondent For The Daily Mail   
   21:00 03 Feb 2016, updated 08:04 04 Feb 2016   
      
   Scientists discovered protein clumps associated with Alzheimer's in the the   
   brains of people thought to have long recovered from a head injury   
   Those with more damage to nerve fibres in the brain had more clumps   
   May indicate why brain injury patients appear to have higher dementia risk   
   Head injuries may lead to the development of dementia many years later, a new   
   study suggests.   
      
   Scientists discovered protein clumps, usually associated with Alzheimer's   
   disease, in the brains of people who were thought to have long ago recovered   
   from a head injury.   
      
   The findings, by researchers from Imperial College London, may help explain   
   why people who have suffered a serious brain injury appear to be at increased   
   risk of dementia.   
      
   Although extensive research now suggests major head injury increases dementia   
   risk in later life, until now scientists did not know why this was.   
      
   People who have suffered a serious brain injury appear to be at increased risk   
   of dementia. Now, scientists have found protein clumps, usually associated   
   with Alzheimer's disease, in the brains of these patients	+4   
   People who have suffered a serious brain injury appear to be at increased risk   
   of dementia. Now, scientists have found protein clumps, usually associated   
   with Alzheimer's disease, in the brains of these patients   
   In the research, published in the journal Neurology, the team studied nine   
   patients with moderate to severe traumatic brain injuries.   
      
   Many had sustained these in road traffic accidents, such as being hit by a   
   car, between 11 months to 17 years prior to the study.   
      
   Although they had no physical disabilities from the injury, many still   
   suffered daily problems with memory and concentration.   
      
   MORE...   
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   Hi-tech scans showed that, like Alzheimer's patients, their brains contained   
   clumps of beta amyloid protein.   
      
   Those who had sustained more damage to nerve fibres in the brain had more of   
   the clumps, or 'plaques'.   
      
   The team also scanned the brains of healthy volunteers, and people with   
   Alzheimer's disease.    
      
    Research is increasingly showing that a blow to the head, such as that   
   sustained in a road accident, triggers biological processes in the brain that   
   burn away in the background for years   
    Lead researcher, Dr Gregory Scott   
      
   The patients with head injury were found to have more amyloid plaques than the   
   healthy volunteers, but fewer than those with Alzheimer's disease.   
      
   Lead researcher Dr Gregory Scott said: 'Although patients may seem to have   
   outwardly made a good recovery, when we see them in clinic years later they   
   can have persistent problems which affect their daily life, for example   
   impairments in concentration    
   and memory.   
      
   'Research is increasingly showing that a blow to the head, such as that   
   sustained in a road accident, triggers biological processes in the brain that   
   burn away in the background for years.'   
      
   Co-author Professor David Sharp added: 'The study is small and the findings   
   preliminary, however, we did find an increased build-up of amyloid plaques in   
   people who had previously sustained a traumatic brain injury.   
      
   'The areas of the brain affected by plaques overlapped those areas affected in   
   Alzheimer's disease, but other areas were involved.   
      
   British scientists discovered protein clumps, usually associated with   
   Alzheimer's disease, in the brains of people who were thought to have long ago   
   recovered from a head injury	+4   
   British scientists discovered protein clumps, usually associated with   
   Alzheimer's disease, in the brains of people who were thought to have long ago   
   recovered from a head injury   
   'People after a head injury are more likely to develop dementia, but it isn't   
   clear why.   
      
   'Our findings suggest traumatic brain injury leads to the development of the   
   plaques which are a well-known feature of Alzheimer's disease.'   
      
   Dr Clare Walton, research manager at the Alzheimer's Society, said: 'The   
   effects of a severe head injury can remain hidden for years.    
      
   'More research is needed to understand why they put you at an increased risk   
   of developing dementia and whether there are ways to reduce that risk once a   
   head injury has occurred.'   
      
   Dr Rosa Sancho, head of research at Alzheimer's Research UK, added: 'Evidence   
   suggests that significant or repeated head injury could lead to an increased   
   risk of dementia, but the biological processes underlying this link are not   
   well understood.   
      
   'The risk factors for Alzheimer's disease are complex with age, genetics, and   
   lifestyle factors all playing a role.'    
      
   HENRY VIII 'MAY HAVE SUFFERED REPEATED TRAUMATIC BRAIN INJURIES SIMILAR TO   
   THOSE EXPERIENCED BY AMERICAN FOOTBALL PLAYERS'   
      
   New research suggests that Henry VIII may have suffered brain damage from a   
   jousting injury	+4   
   New research suggests that Henry VIII may have suffered brain damage from a   
   jousting injury   
   The Tudor King was plagued by memory problems, explosive anger, inability to   
   control impulses, headaches, insomnia -- and even impotence -- that afflicted   
   Henry in the decade before his death in 1547.   
      
   Now US researchers suggest that brain damage from a jousting injury is the   
   best explanation for the King's crazed behaviour in his final years.   
      
   Arash Salardini, behavioural neurologist, co-director of the Yale Memory   
   Clinic and senior author of the study said: 'It is intriguing to think that   
   modern European history may have changed forever because of a blow to the   
   head.'   
      
   The English monarch is best known for his dispute with the Catholic Church   
   over his desire to annul his first marriage to Catherine of Aragon and marry   
   Ann Boleyn.   
      
      
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