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   Research   
      
   Probiotics have a ‘positive effect’ on stress and anxiety: Meta-analysis   
      
      
      
    More studies need to be conducted to determine if the consumption of   
   probiotics could also assist with symptoms of diagnosed clinical depression.   
   ©iStock   
   By Gary Scattergood+ 14-Dec-2016    
   Last updated on 15-Dec-2016 at 03:16 GMT   
      
   Probiotics consumption may have advantageous effects on mental health by   
   lessening the psychological symptoms of perceived stress, depression and   
   anxiety, according to a new systematic review and meta-analysis.   
      
      
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   Published in The Journal of Alternative and Complementary Medicine, the study   
   reviewed the results of seven previous studies which tested for symptoms in   
   over 300 healthy volunteers both before and after supplementation with a   
   probiotic.   
      
   Researchers from Griffith University in Queensland, Australia, wrote:   
   “Interest in the gut–brain axis and emerging evidence that the intestinal   
   microbiota can influence central nervous system function has led to the   
   hypothesis that probiotic    
   supplementation can have a positive effect on mood and psychological symptoms   
   such as depression and anxiety.   
      
   “Although several human clinical trials have investigated this, results have   
   been inconsistent. Therefore, a systematic review and meta-analytic approach   
   was chosen to examine if probiotic consumption has an effect on psychological   
   symptoms.”   
      
   Studies published before July 2016 that were randomized and placebo   
   controlled, and measured preclinical psychological symptoms of depression,   
   anxiety, and perceived stress in healthy volunteers pre and post   
   supplementation with a probiotic were included.   
      
   Seven studies met the inclusion criteria and provided data for nine   
   comparisons.   
      
   “The meta-analysis showed that supplementation with probiotics resulted in a   
   statistically significant improvement in psychological symptoms (standardized   
   mean difference 0.34; 95% confidence interval 0.07–0.61, Z = 2.49)   
   compared with placebo,”   
    they wrote.   
      
   “These results show that probiotic consumption may have a positive effect on   
   psychological symptoms of depression, anxiety, and perceived stress in healthy   
   human volunteers.”   
      
   According to lead author Dr Natalie Colson, more studies need to be conducted   
   to determine if the consumption of probiotics could also assist with symptoms   
   of diagnosed clinical depression.   
      
   “The research into the relationship between the gut and the brain is   
   reasonably new however we are now starting to better understand this ‘gut   
   brain axis’.   
      
   “We don’t know yet how far this could be used in the treatment of   
   depression, however the gut microbiome presents as a potential target for the   
   treatment of cognitive and mood disorders.   
      
   “But it does appear that generally healthy people who are going through   
   stressful periods could certainly benefit from adding probiotics to their   
   diet.”   
      
   Further studies may allow for the development of novel probiotic treatment   
   strategies for gastrointestinal-related disorders that are associated with   
   impaired communication between the gut and brain, said Dr Colson.   
      
       
      
   Source: The Journal of Alternative and Complementary Medicine   
      
   Published online November 2016, ahead of print.   
      
   “Probiotics and Subclinical Psychological Symptoms in Healthy Participants:   
   A Systematic Review and Meta-Analysis”   
      
   Authors: Natalie Colson, et al.   
      
       
      
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   http://mobile.nutraingredients.com/Research/Probiotics-have-a-po   
   itive-effect-on-stress-and-anxiety-Meta-analysis   
      
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