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|    sci.med.psychobiology    |    Dialog and news in psychiatry and psycho    |    4,734 messages    |
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|    Message 4,429 of 4,734    |
|    23x to Oliver Crangle    |
|    Re: The Infection Connection: the possib    |
|    01 Apr 17 04:09:22    |
      From: mjs23x@gmail.com              On Wednesday, August 6, 2014 at 9:55:31 PM UTC-5, Oliver Crangle wrote:       > √       >        >        >        >        > On Sunday, October 5, 2008 7:56:00 PM UTC-5, rpautrey2 wrote:       > > The Infection Connection       > > Examines the possible connection of microorganism with psychological       > > problems. Cause of poor parenting; Technology that helps in revealing       > > damage to the brain.       > >        > > By: Harriet Washington       > > PSYCHOLOGY HAS LONG HELD THAT MENTAL ILLNESS IS BORN OF ADVERSE       > > EXPERIENCES.MORE RECENTLY, RESEARCH HAS POINTED THE FINGER AT FLAWED       > > GENES. NOW A THIRD CULPRIT MAY BE EMERGING: INVASION BY BACTERIA AND       > > VIRUSES.       > >        > > Eight-year-old Seth broke from the grasp of Jane, his harried mother,       > > for the third time in 10 minutes. Tearing across the emergency room,       > > he stopped short, transfixed by a piece of paper lying on the floor.       > > His red-rimmed eyes seemed to bulge from their sockets and his mouth       > > twitched violently, as if he were in pain. Indifferent to Jane's pleas       > > to stop, he proceeded to pick up from the floor every piece of paper,       > > no matter how filthy, with hands that were reddened and raw. It was       > > the state of his hands that had precipitated the trip to the hospital:       > > Seth had spent most of the night in the bathroom, washing them over       > > and over.       > >        > > With his head jerking spasmodically and his fingers pecking at pieces       > > of paper and cigarette butts, the boy resembled some strange overgrown       > > bird. Then, suddenly terrified, he flew back to Jane and began pulling       > > on her arm. "Mommy, Mommy, let's leave!" he whimpered. "They're going       > > to kill us. They're coming!"       > >        > > Jane tried her best to calm him, but she too was beginning to panic.       > > Two days before, Seth had been a perfectly normal little boy whose       > > most serious health problems were the occasional cold or sore throat.       > > He had become mentally ill overnight.       > >        > > What caused Seth's anxiety, his tics, his obsessive-compulsive       > > behavior? Astonishingly, it was probably that minor sore throat, his       > > doctors concluded. Today, scientists are increasingly coming to       > > recognize that the bacteria and viruses that frequently invade our       > > bodies and cause sore throats and other minor ailments may also       > > unleash a host of major mental and emotional illnesses, including       > > anorexia, schizophrenia and obsessive-compulsive disorder.       > >        > > It is a theory sharply at odds with earlier views of the genesis of       > > psychological illness. Followers of Freud long held that mental and       > > emotional trouble is primarily the result of poor parenting,       > > especially by mothers. Indeed, until about 30 years ago,       > > psychoanalysts frequently placed the blame for schizophrenia on       > > "schizophrenogenic" mothers. Obsessive-compulsive disorder, also, was       > > put at Mom's door. "It was thought to be the result of harsh toilet       > > training," observes Susan Swedo, M.D., chief of pediatrics and       > > developmental neuropsychiatry at the National Institutes of Mental       > > Health. But such theories, which added immeasurable guilt to the       > > burdens of parents with mentally ill offspring, have turned out to       > > have little evidence to back them up, most experts now agree.       > >        > > Instead, in recent years, the focus has shifted to genes as the main       > > source of mental illness. Faulty DNA is thought to be at least partly       > > responsible for, among other problems, anxiety and panic disorders,       > > schizophrenia, manic depression and antisocial personality disorder,       > > which is characterized by impulsive, excessively emotional and erratic       > > patterns of interpersonal behavior.       > >        > > Yet genetics doesn't appear to wholly account for the occurrence of       > > major psychiatric ailments. If heredity alone were to blame, identical       > > twins would develop schizophrenia with a high degree of concordance,       > > but in fact in only 40% of cases in which one identical twin has the       > > disease does the other twin have it as well. Autism, though it has       > > been observed to run in families, also strikes five of every 10,000       > > children apparently arbitrarily. Nor can depression and other       > > affective disorders be completely explained by damaged DNA. Says Ian       > > Lipkin, Ph.D., a neuroscientist and microbiologist at the University       > > of California at Irvine: "Genetics doesn't hold the key to       > > understanding how to fit these square pegs into round holes."       > >        > > Bacteria and viruses may be that key, but scientists have been slow to       > > grasp the idea. Consider the case of syphilis, which is caused by the       > > bacterium Treponema pallidum. In its final, or tertiary, stage, the       > > disease can precipitate psychiatric problems like dementia, mania,       > > depression, delusions and Tourette's like tics. Though some scientists       > > suspected a connection between infection with the bacterium and the       > > mental disturbances that may take three to five decades to emerge, the       > > link became widely accepted only in the 1940s after the introduction       > > of the antibiotic penicillin as a treatment for syphilis. In the       > > interim, patients with syphilis who later developed psychiatric       > > problems were often institutionalized as crazy. But even with the link       > > established, Freud's theories were in ascendance and few scientists       > > were willing to consider that microbes might be a common source of       > > other mental illness.       > >        > > Now, decades later, infection has emerged as a prime suspect in       > > psychological illnesses. The inadequacy of genetic and experiential       > > explanations has prompted scientists to look elsewhere--and their gaze       > > has come to rest on physical ailments, such as heart disease, cancers       > > and ulcers, that in some cases have an infectious origin. Could the       > > same be true, they wonder, for mental and emotional ills?       > >        > > Improved technology has made it easier to find out. Since active only       > > when inside other living creatures, microbes are notoriously hard to       > > grow, and therefore study, in the lab, but scientists' ability to do       > > so has increased steadily over the last few decades. Other tools have       > > allowed researchers to see their quarry more clearly. For about a       > > decade, microbiologists have used a technique called polymerase chain       > > reaction, or PCR, to replicate a small piece of genetic material over              [continued in next message]              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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