From: here@is.invalid   
      
   Hope for an effective and inexpensive treatment for the deadly   
   condition sepsis has dimmed following results of a major new study.   
      
   Researchers had hoped that a simple treatment involving infusions of   
   vitamin C, vitamin B1 and steroids would work against a disease that   
   kills an estimated 270,000 people each year in the United States and   
   11 million globally. Sepsis, or blood poisoning, occurs when the body   
   overreacts to infection. It leads to leaky blood vessels, which can   
   cause multiple organ failure.   
   ...   
   ...   
   Coopersmith says the results don't slam the door on the treatment   
   entirely — there's still some chance that it has a modest effect on   
   overall survival, he says, but the study didn't involve enough   
   patients to answer that question. The study found no effect on   
   short-term survival or improvement in certain clinical markers of   
   disease.   
      
   "I don't think we can yet say that there is no impact," Coopersmith   
   says. "I think we could say that the jury's still out on that."   
   ...   
   ...   
   Indeed, Marik, who remains a strong proponent of this approach,   
   rejects the findings of the study. He tells NPR that by his reckoning,   
   patients in the study received treatment far too late in the course of   
   their disease. "It's like giving it to a patient who's dead," he says.   
   "It's of no benefit. The horse was out of the barn miles beforehand."   
      
   Marik gives his patients the vitamin C infusion as quickly as he   
   recognizes signs of sepsis. That's impossible to do in a study in   
   which participants must be enrolled in a study and then randomized   
   into one of the two comparison groups before treatment can begin.   
      
   https://www.npr.org/sections/health-shots/2020/01/17/797058463/v   
   tamin-treatment-for-sepsis-fails-in-large-trial   
      
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    * Origin: you cannot sedate... all the things you hate (1:229/2)