Forums before death by AOL, social media and spammers... "We can't have nice things"
|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
[   << oldest   |   < older   |   list   |   newer >   |   newest >>   ]
|    Message 53,625 of 55,615    |
|    yyy378 to durabol74@gmail.com    |
|    Re: Reduction with Sodium Borohydride    |
|    03 Jul 15 16:43:35    |
      From: donotsentjunk@hotmail.com              On 03/07/2015 14:27, durabol74@gmail.com wrote:       > This reaction takes place in methanol and slowly over 1 hour sodium       borohydride is stirred in. Since heat is generated I assume the sodium       borohydride reacts with the methanol as the reduction takes place but I am       unsure if this is correct? If it doesn'       t react with the methanol it would be nice if I could dissolve the sodium       borohydride in methanol and use a dropping funnel. I have read that the       reduction can also be done with lithium aluminum hydride or sodium, which       might be a better way to go, but I        don't have much for details on these other options.       >       > Brock       >              Sodium borohydride reacts with methanol. The reaction is completed in 90       minutes (in the presence of excess of methanol). But if you want to use       it to reduce aldehyde or ketone, whose reactions are quite fast,       methanol is typically the choice of solvent.              LAH and sodium are stronger reducing agents. Depending on what other       functional groups are present, you may or may not be able to use them.              Use sodium borohydride if you can because it is fast and workup is       simple. LAH very often gives an emulsion during workup.              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
[   << oldest   |   < older   |   list   |   newer >   |   newest >>   ]
(c) 1994, bbs@darkrealms.ca