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|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
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|    Message 53,772 of 55,615    |
|    simplypat@gmail.com to Dale Southard    |
|    Re: Breathing Anti-freeze dangerous?    |
|    31 Jan 16 22:51:54    |
      On Saturday, April 20, 1991 at 8:10:26 PM UTC-5, Dale Southard wrote:       > In article <8260@drutx.ATT.COM> msg@druhi.ATT.COM (GrahamM) writes:       > >Is breathing anti-freeze fumes dangerous?       > >       > >My car has a leak in the heater core, thus the hot air smells like       > >anti-freeze. Can it stay like this for long with no ill effects?       > >       >        > How much do you drink??       >        > The major anti-freeze component is ethylene glycol HOCH2-CH2OH. When       introduced       > into the human body, it is a substrate analog of ethanol and will be acted on       > by the alchohol dehydrogenase (ADH) enzyme, which will convert it to       HO2C-CO2H       > (oxalic adic) over a few steps. Oxalic acid is poisonous.       >        > But, if you drink lots of alcohol, a competitive inhibition "race" is started       > between the ethylene glycol --> oxalic acid and the ethanol --> acetaldehyde       > reactions, giving your body more time to purge the oxalic acid.       >        > This is simular to the mechanism for methanol poinsoning (but the end product       > is formaldehyde).       >        > Note: I am an organic chemist -- any biochem types out there feel free to       > add to/correct the above statements.       >        > Oh, I would doubt that you are getting enough ethylene glycol to be       dangerous,       > but if you are getting hangovers after driving for a while, I would become       > concerned. (Not to mention that anti-freeze hasn't been cheap since the        > ethylene glycol plant blew up, but that is another story).       >        >        >        > --> --> Dale UVa (ds4a@virginia.edu)       My grandson has been breathing fumes antifreeze fumes from heat core damage in       jeep. My eyes would burn and it hurt my throat but I could not make my son or       daughter in law believe it was injuring their son. He will soon be 6 and       they finally believe        he has problems without admitting it is from antifreeze. He can get       uncontrollable in an instant without provocation. They think it is adhd. I       think it goes further than than. where can I get more information. Pat       (simplypat@gmail.com)              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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