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|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
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|    Re: Chemical giants hid dangers of 'fore    |
|    02 Jan 22 03:45:30    |
      From: hrramob@gmail.com              buh buh biden kirjutas Esmaspäev, 17. mai 2021 kl 08:49:48 UTC+3:       > The chemicals, called 6:2 FTOH, are now linked to a range of serious        > health issues, and Americans are still being exposed to them        >        > Chemical giants DuPont and Daikin knew the dangers of a PFAS compound        > widely used in food packaging since 2010, but hid them from the public and        > the Food and Drug Administration (FDA), company studies obtained by the        > Guardian reveal.        >        > The chemicals, called 6:2 FTOH, are now linked to a range of serious        > health issues, and Americans are still being exposed to them in        > greaseproof pizza boxes, carryout containers, fast-food wrappers, and        > paperboard packaging.        >        > Plummeting sperm counts, shrinking penises: toxic chemicals threaten        > humanity        > Erin Brockovich        > Erin Brockovich        > Read more        > The companies initially told the FDA that the compounds were safer and        > less likely to accumulate in humans than older types of PFAS, also known        > as “forever chemicals” and submitted internal studies to support that        > claim.        >        > But Daikin withheld a 2009 study that indicated toxicity to lab rats’        > livers and kidneys, while DuPont in 2012 did not alert the FDA or public        > to new internal data that indicated that the chemical stays in animals’        > bodies for much longer than initially thought.        >        > Science from industry, the FDA and independent researchers now links 6:2        > FTOH to kidney disease, liver damage, cancer, neurological damage,        > developmental problems and autoimmune disorders, while researchers also        > found higher mortality rates among young animals and mothers exposed to        > the chemicals.        >        > Had the FDA seen the data, it is unlikely that it would have approved 6:2        > FTOH, said Maricel Maffini, an independent researcher who studies PFAS in        > food packaging. And though Daikin may have broken the law, it and DuPont,        > which has previously been caught hiding studies that suggest toxicity in        > PFAS, are not facing any repercussions.        >        > “Those things shouldn’t happen, and if they do then there should be        > consequences, but oversight is lax,” Maffini said.        >        > I think people need to be able to rely on the FDA to turn science at the        > agency into real action, and right now that doesn’t seem to be the case        > Tom Neltner        > In 2020, the FDA reached agreements with some major PFAS manufacturers to        > voluntarily stop using 6:2 FTOH compounds in food packaging within five        > years. But documents show that the FDA first became aware of DuPont’s        > hidden study in 2015, and public health advocates say a 10-year timeline        > to reassess and remove the chemical is unacceptable.        >        > Moreover, the FDA phase-out only applies to 6:2 FTOH compounds, and does        > not include other similar “short chain” PFAS, raising questions about        > whether the agency is fully protecting the public from the class of        > potentially toxic chemicals.        >        > “I think people need to be able to rely on the FDA to turn science at the        > agency into real action, and right now that doesn’t seem to be the       case,”        > said Tom Neltner, chemicals policy director with the Environmental Defense        > Fund. He and Maffini obtained the companies’ studies and related documents        > from Daikin’s website and the FDA through Freedom of Information Act        > requests.        >        > The 6:2 FTOH compound is part of a newer generation of “short chain”       PFAS        > that were designed to replace older and supposedly more harmful “long        > chain” PFAS. The industry claims that short chain compounds are uniformly        > safe and “practically non-toxic”. However, independent researchers like        > Erika Schreder, science director for Toxic Free Future, have found that        > PFAS, regardless of chain length, accumulate in the environment and        > humans, and are toxic.        >        > “The fact that we continue to uncover evidence that the current-use PFAS        > have similar toxicity to the [long chain] compounds that have been phased        > out makes a strong argument for regulating harmful chemicals like PFAS as        > a class,” Schreder said.        >        > In a statement to the Guardian, an FDA spokesperson defended the agency’s        > handling of 6:2 FTOH, noting that the studies “do not demonstrate an        > imminent health hazard” and more studies were needed to draw concrete        > conclusions about its safety, and that of other short chain PFAS.        >        > Daikin and Chemours, a company that in 2015 was spun off from DuPont’s        > PFAS division, did not respond to requests for comment.        >        > DuPont hides alarming new data        > Industry reports and communications among the FDA and PFAS producers        > between 2008 and 2020 show how a sequence of inadequate chemical safety        > analyses, hidden studies and lax oversight created a scenario in which        > Americans continue to be exposed to the dangerous compound in food        > packaging.        >        > The 2008 6:2 FTOH studies that DuPont submitted to the FDA monitored the        > impact of high exposure levels to the chemical on two generations of lab        > rats. The animals suffered kidney failure, liver damage, mammary gland        > problems, mottled teeth and other issues. However, DuPont and the FDA felt        > that humans’ exposure would be much lower and, with little supporting        > evidence, believed that the short chain PFAS would not accumulate in human        > bodies, Maffini said.        >        > She called such studies on PFAS “inaccurate and inappropriate” because       the        > chemicals are toxic at “extremely low levels” and are known to       accumulate        > in animals’ bodies.        >        > Indeed, the longer-term DuPont study completed in 2012 found that 6:2 FTOH        > stayed in lab animals’ bodies for longer than previously thought. Still,        > DuPont did not alert the FDA or publish the study.        >        > Though the law does not require companies to make such information public,        > the results strongly suggested a health threat, and DuPont “had an ethical        > obligation to not just publish it, but flag it for the FDA”, Neltner said.        >        > Three years later, DuPont partially summarized its 2012 findings in a        > peer-reviewed 6:2 FTOH study that Maffini said used “cherry-picked” data        > to support its claim that the compound was safe. Though it omitted the        > 2012 study’s details, communications show it caught the attention of the        > FDA, which wrote that the study alerted the agency “to potential               [continued in next message]              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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