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   sci.chem      Chemistry and related sciences      55,615 messages   

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   Message 55,074 of 55,615   
   Treon Verdery to All   
   Longevity technology   
   06 Sep 22 00:56:39   
   
   From: treon3verdery@gmail.com   
      
   Making immunizations function better might go with giving them high amplitude   
   surface charge, I read that the more highly charged the molecule the more   
   macrophages phagocytosised it, I do not know what the dendritic cytes that   
   phagocytosize novel    
   antigens then tell t and b cytes about like to gulp but it is possible they   
   also prefer highly charged molecules, or possibly molecules at a particular   
   charge range; notably along with the possibility of just attaching a highly   
   charged atom or moiety to    
   an antigen, perhaps an anti malaria antigen or an anti pneumonia antigen. is   
   the possibility of just physically coating an antigen with a highly charged   
   molecule coating, or possibly even more effective: find the chemical dendritic   
   cytes most like to    
   gulp, like they could utilize million channel microfluics with a million   
   (6000/load/200 loads) hplc chip separated chemicals, and radiohydrogenate them   
   from the dissociation and swap constant of pH at tritium water then find out   
   which of millions of    
   molecules or moieties dendritic cytes most liked to phagocytosize, then they   
   could attach those to antigens   
      
   Possibly if an antigen is attached to a molecular transport channel or   
   endocytosis causing moiety that works on dendritic cytes the dendritic cytes   
   response to the antigen at telling t and b cytes about it still functions, if   
   so, noting active transport    
   can move 1000 times more molecules into a cyte per moment than passive   
   absorption it is possible dendritic cytes could get 1000 times more antigen   
   activity, or vaccines might even function at 1/100th the usual amount of   
   active ingredient, that could make    
   vaccines an order of magnitutude or two more effective per mg of active   
   ingredient   
      
   It is possible 1000 to 7000 (7 simultaneous different active transport   
   moeities) active transport utilizing vaccines could be functional without   
   refrigeration as 10 half lives are 1/1024 effect and 1000 or 7000 times active   
   transport could make a 7, 14,    
   month half life vaccine last 70, 140, or 300 days; that suggests vaccines   
   which would have been refrigerated could just be transported with the postal   
   utility if they arrive anywhere globally at a month of unrefrigerated transport   
      
   Lyophilized vaccines effectiveness perhaps previously not of utility if it   
   were 1 part per 100 as strong as a refrigerated or live vaccine could function   
   well enough with dendritic cyte transport moieties (1000 times transport) to   
   be functional at    
   refrigerationless vaccine locations   
      
   Multiple transport channels moeities simultaneously on an antigen could make   
   7000 times greater concentration at dendritic cytes from multiple parallel   
   simultaneous transport, it is possible that some transport channel activating   
   moieties omit causing    
   immunuresponse to the moeity like possibly there are glucose, ATP, or unusual   
   yet immunononalerting  self molecules the body always avoids making   
   immunoresponse to that might also be active tranport moieties   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)   

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