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|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
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|    Message 55,078 of 55,615    |
|    Treon Verdery to All    |
|    Rapamycin at 126 ppm that causes 60% gre    |
|    06 Sep 22 05:40:51    |
      From: treon3verdery@gmail.com               it could be that head lifts are moments of noticing, or a pleasant mood       causing the action; as a human taking about 40-60 mg of rapamycin every 24       hours I noticed near sleep hour rapamycin causing being too slightly enthused       and alert to sleep, while        socializing while it was light I perceived I responded to the other person       more promptly, was absent any new or novel emotional valence, and I       experienced a moment when I felt I would have liked it if the person I was       socializing with said funner newer        things more rapidly, but that was like a few seconds; I experienced the       rapamycin as being emotionally non modifying, less stimulating than caffeine,       as well as harmless; it brings up a technology of screening longevity drug       molecular variants on their        projected and actual effects on beneficial voluntary being, form and activity       at human mind and behavior;       Screening a library of longevity drugs as to behavior effects, presence of       being, as well as being physiological wellness heightening or wellness neutral       at 72 hour dosing technology: Screen a library of perhaps 100,000 rapamycin or       other longevity drug        variants at say 33 mice, with sequential screening of the longevity chemicals       to characterize the mice' behavioral, social, fMRI, Positron emission       tomography effects; one different chemical per each 72 hours, with the mice on       video and their tissue        scanned a couple times, is near 300 chemicals quantified per mouse, at a 2019       AD unmedicated mouse; so that is 100k longevity chemicals sequentially       quantified with 40ish mice,       To find pleasant or also neutral behavior and mind effect longevity chemical       molecules the mice could be screened for a few hours of being medicated at       group size: one mouse, before screening any particular chemical molecule on       the 8 mice per molecule        that generates a p<.05 p value, screening the longevity chemicals at mice to       verify beneficial positive or neutral effects on mind and behavior prior to       characterizing and screening them at marmosets makes it so the majority of       mice and the primates have        beneficial, positive, or neutral mind effects and behavior effects; noting       these longevity drugs are technology to benefit humans, that is persons, that       is members of groups of people that is homo sapiens quantifying and screening       to find beneficial        positive effects has actual value;               Noting the longevity chemicals are longevity beneficial, 33 marmosets could       screen 700k molecules or higher amounts sequentially while providing primate       data that could be more predictive of human prosocial, pleasantness of       experience, as well as a        variety of beneficial things like actualized behavior as well as mind and       feeling and sustained presence of benevolence, kindness, empathy behaviors and       ways of mind as well as fMRI of mind (like find 99th percentile benevolent       empathic kind humans, do        fMRI, then at the marmosets note which longevity drug molecules align the fMRI       of the marmosets with those of 99th percentile benevolent, empathic, kind       humans; also at a different quantification find the longevity drugs that       cause, at the marmosets,        actual behavior or also fMRI well above the human actual behavior or also fMRI       at greater than the previous unmedicated median voluntary amount of: sharing,       mating success, above median social fluency, initiating what to a human would       be friendly contact,        big 5 psychology test openness to experience, conscientiousness, mental       wellness, as well as fMRI of creativity              Making longevity drugs globally available, the 24 most frequently occurring       kinds of bacteria as well as fungi that live on wet decaying leaves, also wet       decaying grass are engineerable with CRISPR/cas9 gene drive to make longevity       drugs, the most        frequently occurring soil bacteria, among them actinomycetes, are also gene       drive modifiable to make longevity drugs, making dirt water longevizing,       fungally produced rapamycin, Epithalon AEDG peptide, mTOR decreasers,       senolytic fisetin, e coli        producible antibodies cause insulin like growth factor 1 reduction, decreased       response at the ILGF-1 cytosurface receptor from antibodies on it, are all       producible at organisms and gene drive at organisms that cause wet plant       material to decay; the        person just puts some water on plant parts, puts it in a bag and when the       sweetness peptides the genetic engineering produces make it taste delicious,       perhaps with an enzyme that neutralizes other flavors, the longevity drugs are       orally utilizable                     Also mTOR decreasing active proteins       mTOR receptor response reducing active noncytoglomming antibodies              Screening longevity chemicals and drugs sequentially, when the 100-700k       chemicals are sequentially screened with the mice or also marmosets at a       weather ameliorated (canopied) outdoor mouse dorm as well as outdoor marmoset       dorm then the mammals can move        and socialize heightening social data value              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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