Forums before death by AOL, social media and spammers... "We can't have nice things"
|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
[   << oldest   |   < older   |   list   |   newer >   |   newest >>   ]
|    Message 55,102 of 55,615    |
|    Treon Verdery to All    |
|    Longevity technology    |
|    06 Sep 22 09:57:02    |
      From: treon3verdery@gmail.com              Finding completely new hormetics that increase longevity, healthspan, wellness       and cognitive function               Endoplasmic reticulum hormetic is published. Could there be more, what about a       golgi apparatus hormetic              Catdiocyte hormetic, screen a library of molecules at tissue culture, one       possibility is that at other muscles, exercise is kind of hormetic, microtears       and lactic acid build up, as well as likely other chemicals are produced, if       there are like a        plurality of hormetic or hormeticish chemicals produced at smooth and regular       muscle that is exercised to greatest strength build up or greatest volume       build up then they could make cyto homogenates and also gather between cyte       fluids endocytotically and        between cytes then test them on mice or 3g shrews, it is possible one       exercised beaver or cow could provide sufficient homogenate numerous shrews of       mice              Plasma protein fractions from one unwell monozygotic twin mouse or rat or pig       transfused to the well one to find out if it becomes better than well, a       possibility is screening plasma from mid unwellness as well as first 24 hours       after recovery (absence        of fever, normal motion patterns) monozygotic twins or clones              NR mitochondrial pluralization is hormetic-like, is there a hormetic       mitochondria fuel, screen a library of sugars. Galactose is really bad for       mammals, could there be a molecular variant that is 1/200th as bad with       longevizing, healthspan increasing,        cognition maintaining or increasing effects              Is quadrophospate hormetic (compare ATP)              A possible harmless to experience brain hormetic could be the response of the       brain to longevity producing caloric restriction, among mice that rapidly       regain their full, measured during ad-libitum feeding, cognitive abilities       even while calories        restricted, or heighten them while calorie restricted it is possible to search       for a hormetic response at the CNS, this can also be characterized outside the       CNS at peripheral nerves like lever press velocity before and after caloric       restriction and        after full recover while still being caloric restricted, the volume of       peripheral nervous system material may not be as much, although the greater       structural simplicity might focus hormesis effects on physiochemical rather       than brain structure              Low dose imterleukins, or modified interleukin proteins tested st tissue       culture              Digital gradient matrix lasers on dermis, from 1 mW all the way to 1 Watt, and       different pulse modes and light frequencies, then if any of these are       hormetic. Possibly measurable with a computer camera looking at histology       images to find any regions that        have netter than well histology or the histological morphology of a person 14       years younger, then the cytoreactions from that wattage, pulse method, and       frequency can be characterized to find out if cytes internal to the body       having those hormetic        chemicals upregulated or drug activated causes a beneficial hormetic response       without internal lasers              Cytoplasm mass fractions, like 1000 of them, perhaps from unwell cytes with       95/100 likeliness of full recovery could be screened, when I get a rash there       is a continuum of responses from minutes or hours of non-oozing erythema to       microcrusts, along that        continuum there are likely 95/100 fully recovering cytes, I am not aware of       any rash that seems to heighten wellness on it ceasing, beauty chemical peel       treatments at less than peeling doses could possibly (possibly not) be       characterized as causing        histological hormetic benefit, I have doubts about systemic use, but salicylic       acid makes yeast live 400% longer and I think may have been used at dermal       chemical peels, so perhaps not the salicylic acid as a drug but the       cytochemicals it causes to be        emitted, upregulated, or even decreased, possibly at tissue culture, if       salycilic acid does have a beneficial hormetic effect they could screen a       library to find molecules that have double of an order of magnitude greater       hormetic effect (halogenation or        lipophilicity version combined with hydrophilic version could do it)), I       perceive salycilic acid is water soluble)              Screening a library like these and othets of a few thousand possible new       hormetics could find those with the greatest longevity and healthspan effects,       c elegans doubled lifespan from mitochondrial uncoupling is, to my perception       ascribed to a prenatally        activated lifelong hormetic response              Longevity technology              GSK salycilic acid might be hydrophilic and lipophilic things pass the blood       brain barrier faster, I heard about the acetyl doing that but would propyl       transport the drug even more rapidly, also decanoic acid esters are published       as causing greater        longevity, perhaps a salicylic acid decanoic ester would be beneficial              Has GSK tried combining piperine at its antipyretic an analgesic pills, 2-2000       times dose multipliers are published with piperine and if two or more doses       fit at one pill they could make 24 hour acetaminophen, ibuprofen, and naproxen       with the same sized        pill              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
[   << oldest   |   < older   |   list   |   newer >   |   newest >>   ]
(c) 1994, bbs@darkrealms.ca