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|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
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|    Message 55,104 of 55,615    |
|    Treon Verdery to All    |
|    Eugenics    |
|    06 Sep 22 09:58:50    |
      From: treon3verdery@gmail.com              A one pill one dose genetic optimization, enhancement as well as a la carte       genotype and phenotype pill available at less than one cent each popularizes       beneficial eugenics              Make Stem cells at ovaries with an optimized genome, differentiate to new       oocytes, then deactivate previous unmodified oocytes              Antipyretic pills at the dollar store are less than 1¢ each (.71 ¢), polymer       coated enteric versions full of dry liposomes that bring CRISPR/cas9 or more       advanced technology to restructure stem cells and oocytes utilizing the       lymphatic compartment        omitting first pass metabolism              GnRH linked to another chemical caused more than 100 times preferential       accumulation at the gonads, the CRISPR/cas9 system components could be linked       to a new version of GnRH that omits the usual GnRH effects while concentrating       at the gonads, screen a        library of GnRH molecule variations to find a few that double or greater       gondal concentration              Otimizing the genome of oocytes could benefit from CRISPR/cas9 or a more       advanced technology modifying a large tissue volume like hepatocytes, smooth       muscle cytes, or vascular cytes so that the vascular export of further       CRISPR/cas9 activity to the        ovaries is sufficient to thoroughly remodel the ovaries              The CRISPR/cas9 could make longevity and wellness peptides and proteins (AEDG,       Epithalon, also they could screen dermal beauty peptides to quantify any       beneficial longevity effects) and molecular variants as longevity drugs as       well as quantified as        functional beauty peptides while optimizing the genetics of oocytes. The       combination of a pill that makes a woman or teenager get to be more       beautiful, with clear beautiful skin while benefitting any aspirations of       children she is thinking about having        popularizes eugenics.                     Things that benefit teenagers       Are there acne reducing peptides or proteins; antibiotic peptides are       published, dermal cyte localization technologies could concentrate them at the       dermis. screening a library of non-sex hormone active sex hormoneish molecules       (methoxy moiety?) With        dermal localization and concentration would decrease the effect of endogenous       sex hormones produced during puberty just at the skin, causing preteen clear       skin as well as youthful smooth clear childhood skin to continue throughout       being a teemager, this        could benefit adults as well. 17 alpha estradiol is a nonfeminizing sex       hormone that is published as causing greater longevity, screening a molecule       library of things like 17 alpha estradiol could find a clear skin, child like       youthfulness of skin        molecule.       17 alpha estradiol molecular variant linked to a dermis localization moeity,       with more effective teach to the dermis than minocycline could be a youthful       clear skin technology. 17 alpha estradiol may have a gene therapy advantage as       I perceive there is        some protein chemical like an enzyme that converts some other kind of thing,       possibly estradiol to 17 alpha estradiol, so upregulating the gene that makes       that protein enzyme could be a longevizing, clear skin, gene therapy as well       as germline gene        modification               Beauty and longevity technology       17 alpha estradiol may have a gene therapy advantage as I perceive there is       some protein chemical like an enzyme that converts some other kind of thing,       possibly estradiol to 17 alpha estradiol(AE), so upregulating the gene that       makes that protein enzyme        could be a longevizing(AE), clear skin, gene therapy as well as germline gene       modification. Also benefitting teenagers and adults people could also be       characterized as to the effects of genetically determined sex hormone       multiform ratios (things like 17        b estradiol/17 a estradiol/progestetone ratios) and sex hormone receptor       (where are they located at that genome driven phenotype, how many of them are       there, what is their sensitivity) SNPs, alleles and gene copy numbers'       beneficial effect on clear skin        and beautiful teenage bodies with parents with beautiful bodies who say they       had clear skin as teenagers could be utilized as a genomics science genotype       to be compared with other genotypes to find and contribute body and skin       components to the optimal        genetics of teenage and adult beauty. AEDG linked to beauty peptides, some of       which are tripeptides and seven or eight amino acid beauty peptides would also       build heightened longevity with beauty, I favor germline engineering to build       longevity and        beauty physiological chemistry; among those who might like a pill AEDG       (Epithalon) linked with an enzymatically degradable linker to beauty peptides       or a parallel plurality of beauty peptides, or a sex hormone receptor       activation decreaser, or a        dermally concentratimg antibiotic peptide, could be a Try it for two months,       if you like it, get the gene therapy and germline gene optimization. Notably       at less than 1 cent a pill the gene therapy and germline enhancement pill is       actually more        affordable than a couple months of some different pill               As another possible benefit it might minimize body hair growth               --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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