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|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
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|    Message 55,243 of 55,615    |
|    Treon Verdery to All    |
|    Theoretically it is possible to get the     |
|    01 Oct 22 00:10:24    |
      From: treon3verdery@gmail.com              3d printed needles could have many side pores at the sides of the distal       delivery tip, spreading the high pressure stream into a diffusion area of .1-2       mm at the sides equivalent to plunger pressure standard hypodermic needle       fluid deposition velocities              One possible application of a pressurized hypodermic needle with full needle       flow delivery is cosmetic procedures, aside from the face this could also be       applied at depth to the breasts              1/10 diameter tube with 1/7 diameter fiber optic and sonographically contrast       labelled tip could allow precise micro positioning of the needle, particularly       during cosmetic procedures, if a regular needle is .7mm then this needle would       be .08mm diameter        but still deliver the same amount of fluid, and could be steered to precise       locations              Motorized (electric pump) pipettors are $49-69 on eBay and alibaba so similar       technology could be the same or less, noting only the needle (and perhaps,       like a pipettor, the fluid reservoir) could be disposable              Such a 1/10 diameter pressurized syringe needle with sonography contrast       enhanced tip could be used to inject support and perkiness enhancing chemicals       into the breasts making them match measurements of the person's breasts taken       when they were 15-16,        there are a number of chemicals that could do this, chemicals that are growth       factors for supporting tissues, another possibility is the non carcinogenic       injection of something that causes non-stretch .1-.5mm wide scar tissue deep       at the breast far from        the skin              Similarly pumped 1/10 diameter needles could be used to do medical procedures       on joints or be used at things like chemotherapy of brain and other tumors              It is also possible a 1/10 usual diameter hypodermic needle with a pressurized       fluid delivery would be more comfortable to experience              Treating depression at the developing world could be more effective with 1/10       of 1¢ drugs printed on paper, available without prescription, as described in       my imaged notes, you use an inkjet printer to print 604 1 cm drugged paper       squares on a 11¢        piece of specialized paper, this accompanies the idea that some group of       drugs, when halogenated, ethynyl group modified,and attached to a cytomembrane       passing moiety or peptide each make the drug 10 times more potent, multiplied       that is 1000 times        stronger pharmaceuticals per milligram, so most drugs with a 200 mg dose would       become 200 microgram doses printable with an inkjet printer on 1 centimeter       squares,              Fluorinated ethynylized, cytomembrane passing optimized bupropion (wellbutrin)       could be 10fluorine*10ethynyl*10cytomembtane passing is 1000 times more potent       as mg per dose than wellbutrin, changing it from 68¢ a dose (retail) to 6.8       tenths of one ¢        printable on paper with an inkjet printer, making this available globally       could alleviate depression in 180 million people globally, this        luorine/ethynyl/cytomembrane/inkjet approach could also be used on other       antidepressants but I favor buproprion        because it omits effecting sex drive or even increases it and may be a better       than well drug for those without depression              St johns wort (hypericum extract) is otc and treats depression, they could       find yeast that hydroxylates or replaces hydroxyls with hydrogens       (dehydroxylase) at the st johns wort chemicals like hyperforin then test to       find out if any of these all natural        OTC friendly products are better at relieving depression as well as find out       if any of the metabolites of hypericum found at urine are physiologically       active at reducing depression, I do not know if cow pee extract is       automatically OTC or not, these all        natural products may appeal to those who are shy of doctors or in some       geographic regions              Is there a Trace Amino Acid Receptor based antidepressant, could there be one?       Molecular variations on ADD (attention deficit disorder) drugs might do this       as well as phenylethylamine. (PEA, PEA makes me cheerful at get high dosages              Molecular variants of caffeine that have brain localization moieties or       peptides attached to them could stimulate just particular areas of the brain       or particular kinds of neurons, wikipedia says "caffeine is an antagonist at       all four adenosine receptor        subtypes (A1, A2A, A2B, and A3), although with varying potencies.[6][141] The       affinity (KD) values of caffeine for the human adenosine receptors are 12 μM       at A1, 2.4 μM at A2A, 13 μM at A2B, and 80 μM at A3.[141] Knockout mouse       studies have        specifically implicated antagonism of the A2A receptor as responsible for the       wakefulness-promoting effects of caffeine.[141] Antagonism of adenosine       receptors by caffeine stimulates the medullary vagal, vasomotor, and       respiratory centers, which        increases respiratory rate, reduces heart rate, and constricts blood       vessels.[6] Adenosine receptor antagonism also promotes neurotransmitter       release (e.g., monoamines and acetylcholine), which endows caffeine with its       stimulant effects;[6][142]        adenosine acts as an inhibitory neurotransmitter that suppresses activity in       the central nervous system. " that makes it seem like precluding adenosine       build up at particular locations could have numerous medical benefits, perhaps       an antidepressant that        localizes which prevents jitteriness, grouchiness but keeps depressed people       from day sleeping and makes them cheerful, other possibilities are nootropics       and weight loss drugs              Localization molecular variations of many known and new drugs could produce       many beneficial effects location or cytotype uptake specific and efflux       moieties are previously described, what wikipedia describes as adenosine A1-A3       receptors may differ in        different amounts at different neurons, molecular variants that concentrate at       these preferentially could be localized drugs, also many strategies and       moieties are used to get past the blood brain barrier, so A1-A3 localization       with a BBB pass moiety        like chlorophenoxy could keep the dose low and out of the rest of the body                     [continued in next message]              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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