From: treon3verdery@gmail.com   
      
   Longevity drug: it is published lithocholic acid at 50 micromolar   
   concentration makes yeast live two times longer, screen a library of   
   lithochilic acid molecular variations, some of which are ethynylized and   
   halogated and have cytotransport moieties to    
   find those at 99.99th percentile effectiveness then test them on mice, those   
   100 molecules could be tested on 800-1400 mice as well as human tissue culture   
   and plants; the most hydrophobic bile acids among 6 published as heightening   
   longevity caused the    
   greatest longevity increase suggesting the screened library contain bile acids   
   modified to be 1.5, 7, 24, 60, 100 times as hydrophobic as lithochilic acid,   
   it is perhaps possible that some locations of fluorine at a molecule heighten   
   hydrophobicity (   
   teflonization), and removal of -OH hydroxyl groups heightens lipophilicity so   
   these could also be screened; lithochilic acid heightens the maximum lifespan   
   of yeast making it noteworthy as a human longevity drug   
      
      
      
   The lithocholic acid longevity paper says there are 58 genes effecting   
   longevity in yeast, finding homologs of those genes at mammals, and finding a   
   completely different, complementary, group of longevity increasing genes at   
   mammals could provide new    
   gene product protein drugs as well as genetic enhancement at humans and   
   provide a way to find a model organism, possibly more predictive than mice at   
   the the effectiveness of longevity technologies and drugs   
      
      
      
   Monthly mice and marmosets as longevity, healthspan and wellness screening   
   organisms: mouse producing companies, corporate research departments as well   
   as other mouse used for experimental breeding growing, and existence   
   monitoring facilities could    
   purposefully make sets of mice to be used at experiments, like lomgevity,   
   wellness, and healthspan experiments, that differ as to age at one month each,   
   as a batch, the effect of a longevity chemical on the oldest month would   
   provide the earliest data    
   after a couple months with new data being generated monthly, 8 mice per month   
   provides a p value of .05 for each month and a math way of combining multiple   
   months to provide reportable data like p values could be found; marmosets are   
   primates, and    
   batches of four marmosets at 3 month age intervals could provide primate   
   longevity data at six months, mouse or marmoset age batch experiments would   
   also provide a graph of when, as to their age, a human would most benefit from   
   a new longevity chemical    
   drug or chemical, 8 mice a month at up to 48 months is 384 mice; this also   
   makes a kind of sequential metaanylasis   
      
      
      
   They could also breed organisms with 24% less tissue at a variety of organs   
   and test known longevity molecules on them,   
      
      
      
   At humans the genetics of tissue and organ amounts (volume/mass) could be used   
   to predict the effectiveness of different longevity drugs as well as guide   
   experiments on primate and other mammal models, it is possible a human   
   genetics that favors the    
   function of longevity drugs as well as the effect of different sizes of organs   
   and tissues on longevity is a technology;   
      
      
      
   Organisms with a larger number of longevity genes than those at s cerevisia   
   like other different species of yeast could possibly be found,  making   
   longevity chemical and drug screening on yeast better, they could also   
   genetically engineer yeast to have    
   all the longevity genes at all measured organisms, like humans; also it is   
   possible putting the longevity genes of humans at the genes of mice could   
   produce a better mouse model of human longevity   
      
      
      
   Lithocholic acid at alibaba; 50 micromolar might be kind of like 376g/mole or   
   376 mg per millimole or .00376 mg per micromole to make 50 micromolar   
   solution, 70,000 gram human is then about 70 liters of water or 18 times 70   
   moles as fluid, 3888 moles so    
   a 14.6 mg dose at a human; noting it is possible the GI tract might be   
   effective at filtering lithochilic acid it is possible a liposomal version   
   with transport benefits would be higher function; at humans cholesterol   
   amounts and cancer risk could be    
   effected   
      
      
      
   Some humans make more lithochilic acid than others and have higher cancer   
   risk, when they omit getting cancer do they live longer   
      
      
      
   Rabbits compared with mice   
      
      
      
   Lithochilic acid or a more effective at causing greater longevity engineered   
   into a food plant makes a globally available popular food that could be   
   measured as to its longevity effect on marmosets, possibly at a 3 month   
   partitioned longevity measurement    
   model   
      
      
      
   Longevity technology   
      
      
      
   Making immunizations function better might go with giving them high amplitude   
   surface charge, I read that the more highly charged the molecule the more   
   macrophages phagocytosised it, I do not know what the dendritic cytes that   
   phagocytosize novel    
   antigens then tell t and b cytes about like to gulp but it is possible they   
   also prefer highly charged molecules, or possibly molecules at a particular   
   charge range; notably along with the possibility of just attaching a highly   
   charged atom or moiety to    
   an antigen, perhaps an anti malaria antigen or an anti pneumonia antigen. is   
   the possibility of just physically coating an antigen with a highly charged   
   molecule coating, or possibly even more effective: find the chemical dendritic   
   cytes most like to    
   gulp, like they could utilize million channel microfluics with a million   
   (6000/load/200 loads) hplc chip separated chemicals, and radiohydrogenate them   
   from the dissociation and swap constant of pH at tritium water then find out   
   which of millions of    
   molecules or moieties dendritic cytes most liked to phagocytosize, then they   
   could attach those to antigens   
      
      
      
   Possibly if an antigen is attached to a molecular transport channel or   
   endocytosis causing moiety that works on dendritic cytes the dendritic cytes   
   response to the antigen at telling t and b cytes about it still functions, if   
   so, noting active transport    
   can move 1000 times more molecules into a cyte per moment than passive   
   absorption it is possible dendritic cytes could get 1000 times more antigen   
   activity, or vaccines might even function at 1/100th the usual amount of   
   active ingredient, that could make    
   vaccines an order of magnitutude or two more effective per mg of active   
   ingredient   
      
      
      
      
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