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|    sci.chem    |    Chemistry and related sciences    |    55,615 messages    |
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|    Message 55,425 of 55,615    |
|    Treon Verdery to All    |
|    Bees, humans and any organism with benef    |
|    03 Feb 23 19:37:06    |
      From: treon3verdery@gmail.com              Acarbose blocks the absorption of sugars from the gi tract and makes mice live       about 20% longer, if the longevity effect is caused by blocking sugars then an       epigenetic drug that hypermethylates the genes that make the active sugar       transport chennels at        the cytomembrane, test epigenetic blocking of the 100 most occurring nutrients       and metabolizables at the gi tract membrane to see if blocking any other       common metabolizables like volatile fatty acids, propionate, butrate, and       5-11carbon vfa, also block        lipids, of various molecular sizes, single and double amino acids, the       tertiary chemical products of gi tract bacteria like skatole and colorants,       some of these exclusions could make no uptake epigenetic drugs that increase       lifespan midway between        Acarbose and the 40% longevity increase of enerosorbents. Novel to me is a       very strong light emitting pill or 1/10-1mm light emitting diode microparticle       that uses spectroscopy absorption frequencies or nonsunburn near visible uv or       blue light to        disintegrate organic chemicals, including any antilongevity chemicals or       carcinogens at the gi tract, inductive power and micro antennas, or possibly       very bright nonvisible light through the abdomen and a 40-80 sun concentrator       photovoltaic provide the        watts of laser diode energy. Novelly, at people that eat a lot phototreatment       could reduce the absorbable calories of food, making it so even people that       eat a lot can be at their preferred svelte Ness of body form. Another approach       that uses enzymes        instead of light to detoxify food/gi tract chemicals and reduce absorbable       calories could be at durable b. Durans and other long residence gi tract       flora/probiotic with one dose per 2 centuries of living. To find these ultra       durable multicentury        probiotics they could measure poo from prepubescent bow head whales and bow       head whales that are over 2 centuries old, similarly 400 year durability gi       tract flora/probiotic species could be found comparing juvenile and 400 year       old tortoises. The        multicentury durable probiotics can then be genetically modified to contain a       bunch of different longevity causing peptides, RNA drugs, and actual longevity       producing molecules like the most wellness and possibly longevity producing       plant polyphenols,        anticancer chemicals like sulfofurane, and the active chemicals in longevity       increasing reishi (20% lifespan increase) and lions mane fungi, rapamycin or       better, centrophenoxine, metformin or better, 17 alpha estradiol or better,       circulating gdf-11,        klotho, dcis proteins, any new longevity and juvenescence proteins or peptides       found with parabiosis, the active drug ceramides that are published as causing       10 times reduction and possibly production of wrinkles, noting the possibility       this also reduces        nondermal deep inside the body wrinkling, which depending on efficacy and       physiological harmlessness another separate multicentury probiotic could make       immunoactivating antigens that immunize, thus remove the oldification       chemicals found with parabiosis        procedures, immunizing against multiple forms of pneumonia is published as       reducing human cardiovascular adverse events 40%, so immunizing against       numerous pneumonias, immunize against low density and very low density       lipoproteins/cholesterol, immunize        against those chemicals found at gi tract contents that are deleterious based       on what enterosorbents do, which makes a kind of immunization equivalent to       40% lifespan increase enterosorbents, as a different product it may be       possible to immunoalert brain        glia immunization like effect to any chemicals at the brain that are       deleterious such as when senescent brain cells produce SASP chemicals so       alerting the glia to remove SASP chemicals, but not their source neurons,       could have a 11-37% brain longevity        and juvenescence effect, immunizing against tooth decay and gum infection       noting periodontal disease is associated with cardiovascular disease and       precluding periodontal disease would then make people live longer, I perceive       there may be experimentalthey,        immunize against the illnesses that are absent at specific pathogen free       mammals (specific pathogen free mice live twice as long, and specific pathogen       free marmosets live 11-15% longer, suggesting that precluding not just 14       pathogens at marmosets but        140 pathogens at people with immunization could bring marmosets and people to       over 40% greater longevity, as a new thing it is possible there are enzymes       produced at the body that are actually harmful, one example is the enzyme that       turns testosterone to        dihydrotestosterone, or enzymes involved in low density/lipoprotein synthesis,       enzymes may exist that are coactive with deleterious parabiosis proteins,       insulin like growth factor 1 and any enzymes that make mtor/mtor1 chemistry       occur could be immunized        against, enzymes that support the conversion of harmless physiochemicals to       low density cholesterol, enzymes associated with the spleen, noting       splenectomy makes mice live 14% longer, immunizing against any liver enzymes       that degrade beneficial chemicals        like the juvenescent parabiosis chemicals, and immunizing against enzymes that       degrade dietary fruit and vegetable polyphenols or other beneficial       phytonutrients, any enzymes that are part of the process the first       multicentury durability probiotic that        just makes beneficial things could also make epithalon, thymalin, beauty       peptides and regeneration peptides, epigenetic up regulation of the 11       sequential most limiting factor enzymes at the TCA ATP production cycle could       cause juvenescence and longevity        increase comparable to, or much higher than nucleotide NMN which causes       longevity increase and young rotarod performance at old mice, the probiotic       bacteria could also make liver enzymes that are effective at neutralizing       organic chemical carcinogens,        removing 90-99% of the most common carcinogens before they reach the       circulatory system and the liver which cleans up the rest. epigenetic       modifying peptides and                     [continued in next message]              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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