XPost: talk.origins, free.metaphysics, talk.religion.pantheism   
   From: rokimoto557@gmail.com   
      
   On 9/7/2025 8:53 PM, Dale wrote:   
   >   
   >   
   > random mutation ?   
   >   
   > https://en.wikipedia.org/wiki/Randomness   
   >   
   > https://en.wikipedia.org/wiki/Evolution   
   >   
   > https://en.wikipedia.org/wiki/Randomized_controlled_trial   
   >   
   >   
   > is random really a definition of disorder ?   
   >   
   > https://en.wikipedia.org/wiki/Entropy   
   >   
   > https://en.wikipedia.org/wiki/Uncertainty_principle   
   >   
   >   
   > induction ?   
   >   
   > if disorder then evolution ?   
   >   
   >   
   > not a hypothesis of deduction as reversed induction ?   
   >   
   > https://en.wikipedia.org/wiki/Hypothesis   
   >   
   > https://en.wikipedia.org/wiki/Reversible_computing   
   >   
   > if evolution then disorder ?   
   >   
   >   
   > even if it was a hypothesis, it is not a theory because it isn't   
   > testable until life at full evolution can test it by disordering   
   > everything including it self ?   
   >   
   > no data left to statistically analyze ?   
   >   
   >   
   Whatever you are trying to do here it doesn't matter.  We already   
   understand that mutations are not "random" as in the usual probability   
   estimation methods sense.  We know that transcribed sequences are more   
   prone to mutation.  The act of making RNA exposes the DNA to higher   
   mutation rates.  We know that CpG dinucleotides suffer mutations at a   
   higher rate than other dinucleotide combinations.  Certain sequences   
   suffer mutations more often than others.  There is a single base   
   substitution that occurs in around 1 in 14,000 live births.  We know   
   this because it causes a dominant phenotype (achondroplastic dwarfism,   
   munchkin dwarfs) and in around 98% of the changes at this site the same   
   base substitution occurs, but we do not know why.  The mutation rate for   
   most of your genome is around 1 X 10^-8 and this site mutates at around   
   1 X 10^-4.  When people claim random mutation they really mean   
   arbitrary.  We know that they are not truly random, but when they occur   
   is arbitrary and unpredictable.   
      
   Ron Okimoto   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)