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|    talk.origins    |    Evolution versus creationism (sometimes    |    142,579 messages    |
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|    MarkE to All    |
|    "Thermodynamic Limitations on the Natura    |
|    17 Jul 25 15:44:28    |
      From: me22over7@gmail.com               From this recent EN article:       https://evolutionnews.org/2025/07/new-article-from-james-tour-un       ermines-a-pillar-of-origin-of-life-theories/              'In comparison to a protein’s half-life, the rate of polypeptide chain       elongation under prebiotic conditions is very long. Yang et al. (2025)       identify numerous barriers to sustained polypeptide growth, including       the formation of non-peptide linkages and cyclic structures, stringent       environmental requirements, and unfavorable thermodynamics. Their       analysis establishes that the rate of growth must be far smaller than       one added amino acid per chain per day."              "Even assuming one addition each day, synthesizing a protein of 200       amino acids would require over six months. However, the growing chain       would almost certainly degrade in a much shorter time span. The       challenge is even greater for RNA, which has a significantly shorter       half-life and encounters additional chemical and structural hurdles       during formation."              Paper here: https://sciendo.com/article/10.2478/biocosmos-2025-0010              No doubt this paper will be critiqued and disputed, but it is I think an       example of the ongoing scrutiny and developing fundamental challenges to       OoL. My prediction is these will continue to emerge, weakening       materialistic abiogenesis and strengthening ID's core claim.              --- SoupGate-Win32 v1.05        * Origin: you cannot sedate... all the things you hate (1:229/2)    |
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