From: me@yahoo.com   
      
   On 2025-07-18 04:30:11 +0000, MarkE said:   
      
   > On 18/07/2025 5:25 am, Kalkidas wrote:   
   >> On 7/16/2025 10:44 PM, MarkE wrote:   
   >>>  From this recent EN article: https://evolutionnews.org/2025/07/new-   
   >>> article-from-james-tour-undermines-a-pillar-of-origin-of-life-theories/   
   >>>   
   >>> 'In comparison to a protein’s half-life, the rate of polypeptide chain   
   >>> elongation under prebiotic conditions is very long. Yang et al. (2025)   
   >>> identify numerous barriers to sustained polypeptide growth, including   
   >>> the formation of non-peptide linkages and cyclic structures, stringent   
   >>> environmental requirements, and unfavorable thermodynamics. Their   
   >>> analysis establishes that the rate of growth must be far smaller than   
   >>> one added amino acid per chain per day."   
   >>>   
   >>> "Even assuming one addition each day, synthesizing a protein of 200   
   >>> amino acids would require over six months. However, the growing chain   
   >>> would almost certainly degrade in a much shorter time span. The   
   >>> challenge is even greater for RNA, which has a significantly shorter   
   >>> half-life and encounters additional chemical and structural hurdles   
   >>> during formation."   
   >>>   
   >>> Paper here: https://sciendo.com/article/10.2478/biocosmos-2025-0010   
   >>>   
   >>> No doubt this paper will be critiqued and disputed, but it is I think   
   >>> an example of the ongoing scrutiny and developing fundamental   
   >>> challenges to OoL. My prediction is these will continue to emerge,   
   >>> weakening materialistic abiogenesis and strengthening ID's core claim.   
   >>   
   >> Note that the replies to your post offer no refutation of any of the   
   >> points of the paper, Just name-calling and genetic fallacies.   
   >>   
   >   
   > Noted; not unusual. Pity - Athel could add some content to this discussion.   
      
   Of course I could, because I know what the laws of thermodynamics say,   
   but what would be the point?   
      
   --   
   athel cb : Biochemical Evolution, Garland Science, 2016   
      
   --- SoupGate-Win32 v1.05   
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