From: rokimoto557@gmail.com   
      
   On 7/17/2025 11:25 PM, MarkE wrote:   
   > On 18/07/2025 12:48 am, RonO wrote:   
   >> On 7/17/2025 12:44 AM, MarkE wrote:   
   >>>  From this recent EN article: https://evolutionnews.org/2025/07/new-   
   >>> article-from-james-tour-undermines-a-pillar-of-origin-of-life-theories/   
   >>>   
   >>> 'In comparison to a protein’s half-life, the rate of polypeptide   
   >>> chain elongation under prebiotic conditions is very long. Yang et al.   
   >>> (2025) identify numerous barriers to sustained polypeptide growth,   
   >>> including the formation of non-peptide linkages and cyclic   
   >>> structures, stringent environmental requirements, and unfavorable   
   >>> thermodynamics. Their analysis establishes that the rate of growth   
   >>> must be far smaller than one added amino acid per chain per day."   
   >>>   
   >>> "Even assuming one addition each day, synthesizing a protein of 200   
   >>> amino acids would require over six months. However, the growing chain   
   >>> would almost certainly degrade in a much shorter time span. The   
   >>> challenge is even greater for RNA, which has a significantly shorter   
   >>> half-life and encounters additional chemical and structural hurdles   
   >>> during formation."   
   >>>   
   >>> Paper here: https://sciendo.com/article/10.2478/biocosmos-2025-0010   
   >>>   
   >>> No doubt this paper will be critiqued and disputed, but it is I think   
   >>> an example of the ongoing scrutiny and developing fundamental   
   >>> challenges to OoL. My prediction is these will continue to emerge,   
   >>> weakening materialistic abiogenesis and strengthening ID's core claim.   
   >>>   
   >>>   
   >> It is only an example of the continuation of Biblical creationist's   
   >> denial of the fact that nature is not Biblical.   
   >>   
   >> Tour really doesn't care if some god was responsible for making these   
   >> initial polymers (if they ever needed to exist because no one knows   
   >> what the first molecular self replicators were).  That god is not the   
   >> god described in the Bible.  Like you, he only wants to deny reality.   
   >>   
   >> Has anyone proposed that the origin of life depends on condensation   
   >> polymerization in solution?   
   >   
   > Yes. You know...primordial soup, warm little pond, early ocean,   
   > hydrothermal vents, etc?   
      
   You should read the Yang et al., 2025 review article that the ID perps   
   cite in the scam article that you link to.   
      
   They go over the alternatives that are not subject to the slow   
   polymerization.  So the ID perp knew about the alternatives before they   
   wrote the bogus article, and only cite Yang et al. 2025 for the expected   
   time of polymerization in solution when Yang extensively reviews the   
   mineral catalyst option and notes the experimental sucesses.   
   Essentially they were quote mining, and Yang obviously was talking about   
   the options where the reaction is facilitated.   
      
   https://link.springer.com/article/10.1007/s00239-025-10237-9   
   Really, they cite an article noting that the time limit doesn't exist   
   because there are catalytic options.   
      
   >   
   > RNA likely wasn't what the first self   
   >> replicators were made of.  The RNA world would have come after there   
   >> were simple molecular self replicators.  Everything that I recall has   
   >> been looking for catalytic surfaces that could be mineral or part   
   >> mineral to make macromolecules.  I do not think that anyone ever   
   >> wanted to depend on amino acids or nucleotides combining in solution.   
   >> Yes, the reaction will spontaneously occur, but no one was depending   
   >> on it to happen to form long polymers.  If the long polymers were self   
   >> replicators they would have the catalytic ability to make more long   
   >> polymers.  They would not be subject to the Tour's time limit, and if   
   >> the first ploymers were formed by the catalytic activity of clay or   
   >> other mineral surfaces they would not be subject to Tour's time limit.   
   >>   
   >> Google definition of catalysis:   
   >> Catalysis is the process of increasing the rate of a chemical reaction   
   >> by adding a substance called a catalyst, which itself is not consumed   
   >> in the reaction. Catalysts work by providing an alternative reaction   
   >> pathway with a lower activation energy, making it easier for the   
   >> reaction to proceed. Catalysis is crucial in many industrial   
   >> processes, as well as in biological systems like the human body.   
   >>   
   >> Tour knows that there never was any ID creation science, and he knows   
   >> that what he is doing is not support for his religious beliefs.  It is   
   >> only denial for the sake of denial.   
   >>   
   >> You do owe, at least, me the explanation that I requested after   
   >> answering all your denial posts.   
   >   
   > I do appreciate your consistent engagement, and would like to be as   
   > upfront as I can, so here you are:   
   >   
   >>   
   >> REPOST:   
   >> MarkE, you likely owe everyone a straight forward statement on how you   
   >> intend to integrate the god that would have been responsible for   
   >> setting chirality into the initial lifeforms over 3 billion years ago   
      
   [continued in next message]   
      
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