From: rokimoto557@gmail.com   
      
   On 7/19/2025 7:04 AM, MarkE wrote:   
   > On 19/07/2025 12:45 am, RonO wrote:   
   >> On 7/17/2025 11:25 PM, MarkE wrote:   
   >>> On 18/07/2025 12:48 am, RonO wrote:   
   >>>> On 7/17/2025 12:44 AM, MarkE wrote:   
   >>>>>  From this recent EN article: https://evolutionnews.org/2025/07/   
   >>>>> new- article-from-james-tour-undermines-a-pillar-of-origin-of-life-   
   >>>>> theories/   
   >>>>>   
   >>>>> 'In comparison to a protein’s half-life, the rate of polypeptide   
   >>>>> chain elongation under prebiotic conditions is very long. Yang et   
   >>>>> al. (2025) identify numerous barriers to sustained polypeptide   
   >>>>> growth, including the formation of non-peptide linkages and cyclic   
   >>>>> structures, stringent environmental requirements, and unfavorable   
   >>>>> thermodynamics. Their analysis establishes that the rate of growth   
   >>>>> must be far smaller than one added amino acid per chain per day."   
   >>>>>   
   >>>>> "Even assuming one addition each day, synthesizing a protein of 200   
   >>>>> amino acids would require over six months. However, the growing   
   >>>>> chain would almost certainly degrade in a much shorter time span.   
   >>>>> The challenge is even greater for RNA, which has a significantly   
   >>>>> shorter half-life and encounters additional chemical and structural   
   >>>>> hurdles during formation."   
   >>>>>   
   >>>>> Paper here: https://sciendo.com/article/10.2478/biocosmos-2025-0010   
   >>>>>   
   >>>>> No doubt this paper will be critiqued and disputed, but it is I   
   >>>>> think an example of the ongoing scrutiny and developing fundamental   
   >>>>> challenges to OoL. My prediction is these will continue to emerge,   
   >>>>> weakening materialistic abiogenesis and strengthening ID's core claim.   
   >>>>>   
   >>>>>   
   >>>> It is only an example of the continuation of Biblical creationist's   
   >>>> denial of the fact that nature is not Biblical.   
   >>>>   
   >>>> Tour really doesn't care if some god was responsible for making   
   >>>> these initial polymers (if they ever needed to exist because no one   
   >>>> knows what the first molecular self replicators were).  That god is   
   >>>> not the god described in the Bible.  Like you, he only wants to deny   
   >>>> reality.   
   >>>>   
   >>>> Has anyone proposed that the origin of life depends on condensation   
   >>>> polymerization in solution?   
   >>>   
   >>> Yes. You know...primordial soup, warm little pond, early ocean,   
   >>> hydrothermal vents, etc?   
   >>   
   >> You should read the Yang et al., 2025 review article that the ID perps   
   >> cite in the scam article that you link to.   
   >>   
   >> They go over the alternatives that are not subject to the slow   
   >> polymerization.  So the ID perp knew about the alternatives before   
   >> they wrote the bogus article, and only cite Yang et al. 2025 for the   
   >> expected time of polymerization in solution when Yang extensively   
   >> reviews the mineral catalyst option and notes the experimental   
   >> sucesses. Essentially they were quote mining, and Yang obviously was   
   >> talking about the options where the reaction is facilitated.   
   >>   
   >> https://link.springer.com/article/10.1007/s00239-025-10237-9   
   >> Really, they cite an article noting that the time limit doesn't exist   
   >> because there are catalytic options.   
   >>   
   >>>   
   >>> RNA likely wasn't what the first self   
   >>>> replicators were made of.  The RNA world would have come after there   
   >>>> were simple molecular self replicators.  Everything that I recall   
   >>>> has been looking for catalytic surfaces that could be mineral or   
   >>>> part mineral to make macromolecules.  I do not think that anyone   
   >>>> ever wanted to depend on amino acids or nucleotides combining in   
   >>>> solution. Yes, the reaction will spontaneously occur, but no one was   
   >>>> depending on it to happen to form long polymers.  If the long   
   >>>> polymers were self replicators they would have the catalytic ability   
   >>>> to make more long polymers.  They would not be subject to the Tour's   
   >>>> time limit, and if the first ploymers were formed by the catalytic   
   >>>> activity of clay or other mineral surfaces they would not be subject   
   >>>> to Tour's time limit.   
   >>>>   
   >>>> Google definition of catalysis:   
   >>>> Catalysis is the process of increasing the rate of a chemical   
   >>>> reaction by adding a substance called a catalyst, which itself is   
   >>>> not consumed in the reaction. Catalysts work by providing an   
   >>>> alternative reaction pathway with a lower activation energy, making   
   >>>> it easier for the reaction to proceed. Catalysis is crucial in many   
   >>>> industrial processes, as well as in biological systems like the   
   >>>> human body.   
   >>>>   
   >>>> Tour knows that there never was any ID creation science, and he   
   >>>> knows that what he is doing is not support for his religious   
   >>>> beliefs.  It is only denial for the sake of denial.   
   >>>>   
   >>>> You do owe, at least, me the explanation that I requested after   
   >>>> answering all your denial posts.   
   >>>   
   >>> I do appreciate your consistent engagement, and would like to be as   
      
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