From: rokimoto557@gmail.com   
      
   On 7/19/2025 10:00 AM, RonO wrote:   
   > On 7/19/2025 7:04 AM, MarkE wrote:   
   >> On 19/07/2025 12:45 am, RonO wrote:   
   >>> On 7/17/2025 11:25 PM, MarkE wrote:   
   >>>> On 18/07/2025 12:48 am, RonO wrote:   
   >>>>> On 7/17/2025 12:44 AM, MarkE wrote:   
   >>>>>>  From this recent EN article: https://evolutionnews.org/2025/07/   
   >>>>>> new- article-from-james-tour-undermines-a-pillar-of-origin-of-   
   >>>>>> life- theories/   
   >>>>>>   
   >>>>>> 'In comparison to a protein’s half-life, the rate of polypeptide   
   >>>>>> chain elongation under prebiotic conditions is very long. Yang et   
   >>>>>> al. (2025) identify numerous barriers to sustained polypeptide   
   >>>>>> growth, including the formation of non-peptide linkages and cyclic   
   >>>>>> structures, stringent environmental requirements, and unfavorable   
   >>>>>> thermodynamics. Their analysis establishes that the rate of growth   
   >>>>>> must be far smaller than one added amino acid per chain per day."   
   >>>>>>   
   >>>>>> "Even assuming one addition each day, synthesizing a protein of   
   >>>>>> 200 amino acids would require over six months. However, the   
   >>>>>> growing chain would almost certainly degrade in a much shorter   
   >>>>>> time span. The challenge is even greater for RNA, which has a   
   >>>>>> significantly shorter half-life and encounters additional chemical   
   >>>>>> and structural hurdles during formation."   
   >>>>>>   
   >>>>>> Paper here: https://sciendo.com/article/10.2478/biocosmos-2025-0010   
   >>>>>>   
   >>>>>> No doubt this paper will be critiqued and disputed, but it is I   
   >>>>>> think an example of the ongoing scrutiny and developing   
   >>>>>> fundamental challenges to OoL. My prediction is these will   
   >>>>>> continue to emerge, weakening materialistic abiogenesis and   
   >>>>>> strengthening ID's core claim.   
   >>>>>>   
   >>>>>>   
   >>>>> It is only an example of the continuation of Biblical creationist's   
   >>>>> denial of the fact that nature is not Biblical.   
   >>>>>   
   >>>>> Tour really doesn't care if some god was responsible for making   
   >>>>> these initial polymers (if they ever needed to exist because no one   
   >>>>> knows what the first molecular self replicators were).  That god is   
   >>>>> not the god described in the Bible.  Like you, he only wants to   
   >>>>> deny reality.   
   >>>>>   
   >>>>> Has anyone proposed that the origin of life depends on condensation   
   >>>>> polymerization in solution?   
   >>>>   
   >>>> Yes. You know...primordial soup, warm little pond, early ocean,   
   >>>> hydrothermal vents, etc?   
   >>>   
   >>> You should read the Yang et al., 2025 review article that the ID   
   >>> perps cite in the scam article that you link to.   
   >>>   
   >>> They go over the alternatives that are not subject to the slow   
   >>> polymerization.  So the ID perp knew about the alternatives before   
   >>> they wrote the bogus article, and only cite Yang et al. 2025 for the   
   >>> expected time of polymerization in solution when Yang extensively   
   >>> reviews the mineral catalyst option and notes the experimental   
   >>> sucesses. Essentially they were quote mining, and Yang obviously was   
   >>> talking about the options where the reaction is facilitated.   
   >>>   
   >>> https://link.springer.com/article/10.1007/s00239-025-10237-9   
   >>> Really, they cite an article noting that the time limit doesn't exist   
   >>> because there are catalytic options.   
   >>>   
   >>>>   
   >>>> RNA likely wasn't what the first self   
   >>>>> replicators were made of.  The RNA world would have come after   
   >>>>> there were simple molecular self replicators.  Everything that I   
   >>>>> recall has been looking for catalytic surfaces that could be   
   >>>>> mineral or part mineral to make macromolecules.  I do not think   
   >>>>> that anyone ever wanted to depend on amino acids or nucleotides   
   >>>>> combining in solution. Yes, the reaction will spontaneously occur,   
   >>>>> but no one was depending on it to happen to form long polymers.  If   
   >>>>> the long polymers were self replicators they would have the   
   >>>>> catalytic ability to make more long polymers.  They would not be   
   >>>>> subject to the Tour's time limit, and if the first ploymers were   
   >>>>> formed by the catalytic activity of clay or other mineral surfaces   
   >>>>> they would not be subject to Tour's time limit.   
   >>>>>   
   >>>>> Google definition of catalysis:   
   >>>>> Catalysis is the process of increasing the rate of a chemical   
   >>>>> reaction by adding a substance called a catalyst, which itself is   
   >>>>> not consumed in the reaction. Catalysts work by providing an   
   >>>>> alternative reaction pathway with a lower activation energy, making   
   >>>>> it easier for the reaction to proceed. Catalysis is crucial in many   
   >>>>> industrial processes, as well as in biological systems like the   
   >>>>> human body.   
   >>>>>   
   >>>>> Tour knows that there never was any ID creation science, and he   
   >>>>> knows that what he is doing is not support for his religious   
   >>>>> beliefs.  It is only denial for the sake of denial.   
   >>>>>   
   >>>>> You do owe, at least, me the explanation that I requested after   
   >>>>> answering all your denial posts.   
   >>>>   
      
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