From: me22over7@gmail.com   
      
   Q6. “Minimum viable MET”: what is the smallest set of components that   
   can yield directionally sensitive, tethered mechanotransduction (even if   
   low fidelity)?   
      
   A. https://chatgpt.com/s/t_693fff94b4e881919740963d356fec8a   
      
   A “minimum viable” directionally sensitive, tethered MET system (even   
   low fidelity) requires three functional modules:   
      
   a force-bearing extracellular tether with defined polarity,   
      
   a mechanically gated cation pore at one end of that tether, and   
      
   a coupler/scaffold that converts tether tension into channel gating (and   
   keeps the complex in the right place).   
      
   ...   
      
   --- SoupGate-Win32 v1.05   
    * Origin: you cannot sedate... all the things you hate (1:229/2)