From: 69jpil69@gmail.com
On Sat, 27 Dec 2025 22:44:09 +1100, MarkE wrote:
>On 24/12/2025 7:27 am, John Harshman wrote:
>> On 12/22/25 11:16 PM, MarkE wrote:
>>> This is a rejection of gene-centric causal supremacy, and an argument
>>> for multi-level, bidirectional causation and information sourcing. The
>>> cell (zygote in the first instance) in its entirety e.g. proteins,
>>> RNA, sugars etc and their structural arrangement (cytoplasm,
>>> organelles, membrane etc) and interactions regulate and control gene
>>> expression. The distribution of these in the cell represent essential
>>> "analogue" information. That's where I think the unaccounted
>>> information is to be found.
>>
>> That doesn't work. For one thing, almost all the information about
>> different sorts of cells doesn't reach the germ line, other than through
>> the genome that gives rise to those sorts. The ovum does contain certain
>> maternal proteins and transcripts that help to get development going,
>> but those are specified by the maternal genome, and the rest of the
>> zygote's cellular contents are quickly recycles using transcription and
>> translation from the zygote's genome. Whether a zygote turns into a
>> chimp or a human is determined by the contents of its genome, not all
>> that other stuff.
>
>"Whether a zygote turns into a chimp or a human is determined by the
>contents of its genome, not all that other stuff."
>
>Are you implying by this claim that, in principle, human DNA could be
>inserted in a chimp ovum or vice-versa, to produce a human or chimp?
Keep in mind mtDNA, which is part of cellular mitochondria, is also
part of ova's genetic package.
--
To know less than we don't know is the nature of most knowledge
--- SoupGate-Win32 v1.05
* Origin: you cannot sedate... all the things you hate (1:229/2)
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